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Respiratory syncytial virus contributes to more severe respiratory morbidity than influenza in children < 2 years during seasonal influenza peaks

tetano

Editor, Senior Moderator
Infection. 2019 Feb 23. doi: 10.1007/s15010-019-01287-5. [Epub ahead of print]
[h=1]Respiratory syncytial virus contributes to more severe respiratory morbidity than influenza in children < 2 years during seasonal influenza peaks.[/h] Amini R[SUP]1[/SUP], Gilca R[SUP]2,[/SUP][SUP]3,[/SUP][SUP]4[/SUP], Boucher FD[SUP]3,[/SUP][SUP]4[/SUP], Charest H[SUP]2[/SUP], De Serres G[SUP]2,[/SUP][SUP]3,[/SUP][SUP]4[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] [h=4]PURPOSE:[/h] To compare the frequency and the severity of influenza and respiratory syncytial viruses (RSV) infections among children < 24 months hospitalized with respiratory symptoms.
[h=4]METHODS:[/h] Data from a prospective study conducted during the peak of five influenza seasons in the Province of Quebec, Canada were used.
[h=4]RESULTS:[/h] We detected higher frequency of RSV compared to influenza viruses (55.3% vs. 16.3%). Radiologically confirmed pneumonia was significantly more frequent in children with RSV (39%) than those with influenza (18%) and the clinical course was more severe in RSV than influenza-infected children, especially among infants < 3 months.
[h=4]CONCLUSION:[/h] Even during peak weeks of influenza season, we found a higher burden and severity of RSV compared with influenza virus disease in hospitalized children < 24 months.


[h=4]KEYWORDS:[/h] Children; Detection; Hospitalization; Influenza; Respiratory syncytial virus (RSV)

PMID: 30798473 DOI: 10.1007/s15010-019-01287-5
 
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