tetano
Editor, Senior Moderator
J Infect. 2016 May 10. pii: S0163-4453(16)30046-9. doi: 10.1016/j.jinf.2016.04.019. [Epub ahead of print]
[h=1]Respiratory viruses and children.[/h] Heikkinen T[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Respiratory viruses place a great disease burden especially on the youngest children in terms of high rates of infection, bacterial complications and hospitalizations. In developing countries, some viral infections are even associated with substantial mortality in children. The interaction between viruses and bacteria is probably much more common and clinically significant than previously understood. Respiratory viruses frequently initiate the cascade of events that ultimately leads to bacterial infection. Effective antiviral agents can substantially shorten the duration of the viral illness and prevent the development of bacterial complications. Viral vaccines have the potential to not only prevent the viral infection but also decrease the incidence of bacterial complications. At present, antivirals and vaccines are only available against influenza viruses, but new vaccines and antivirals against other viruses, especially for RSV, are being developed.
Copyright ? 2016 The British Infection Association. Published by Elsevier Ltd. All rights reserved.
[h=4]KEYWORDS:[/h] Antiviral; Bacteria; Influenza; Oseltamivir; Otitis media; Pneumonia; Respiratory syncytial virus; Vaccine; Virus
PMID: 27177731 [PubMed - as supplied by publisher]
[h=1]Respiratory viruses and children.[/h] Heikkinen T[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Respiratory viruses place a great disease burden especially on the youngest children in terms of high rates of infection, bacterial complications and hospitalizations. In developing countries, some viral infections are even associated with substantial mortality in children. The interaction between viruses and bacteria is probably much more common and clinically significant than previously understood. Respiratory viruses frequently initiate the cascade of events that ultimately leads to bacterial infection. Effective antiviral agents can substantially shorten the duration of the viral illness and prevent the development of bacterial complications. Viral vaccines have the potential to not only prevent the viral infection but also decrease the incidence of bacterial complications. At present, antivirals and vaccines are only available against influenza viruses, but new vaccines and antivirals against other viruses, especially for RSV, are being developed.
Copyright ? 2016 The British Infection Association. Published by Elsevier Ltd. All rights reserved.
[h=4]KEYWORDS:[/h] Antiviral; Bacteria; Influenza; Oseltamivir; Otitis media; Pneumonia; Respiratory syncytial virus; Vaccine; Virus
PMID: 27177731 [PubMed - as supplied by publisher]