tetano
Editor, Senior Moderator
Rev Esp Anestesiol Reanim
. 2021 Apr 8;S0034-9356(21)00136-5.
doi: 10.1016/j.redar.2021.03.009. Online ahead of print.
SARS-CoV-2 infection. Descriptive analysis of a selected case series
[Article in English, Spanish]
C L Errando[SUP] 1 [/SUP], C S Romero-García[SUP] 1 [/SUP], M J Hernández-Cádiz[SUP] 1 [/SUP], M Á Pallardó-López[SUP] 1 [/SUP], J Puig[SUP] 1 [/SUP]
Affiliations
Abstract
Objectives: COVID-19 was declared pandemic by March 2020. Clinical, analytical, and radiological findings have been reported. Detailed different evolution of patients of the same local outbreak has been scarcely reported. We report 6 selected cases of such an evolution.
Clinical cases: The clinical, radiological, analytical evolution of 6patients is reported. Patients were selected as it were epidemiological close contacts, and showed particular different clinical evolution.
Results: The clinical course at the start of infection (first week) was similar among patients. In relationship with clinical evolution, middle to severe course were related with inflammation markers levels evolution (D-dimer, IL-6, ferritin, lymphocytes count, etc.). Specially lung alterations were observed, but neurological/neuropsychiatric findings are still common. In evolution, 2patients showed middle symptoms, but the 2most severely affected died.
Conclusions: It remains to be elucidated the different evolutive pathways and outcomes of COVD-19. In our 6patients of the same local outbreak, clinical, laboratory and radiological features were different. We discuss some aspects of the pathophysiology of the disease, other than the widely described of the respiratory system.
Keywords: Brote epidémico; COVID-19; Complicaciones; Complications; Coronavirus; ICU; Outbreak; UCI.
. 2021 Apr 8;S0034-9356(21)00136-5.
doi: 10.1016/j.redar.2021.03.009. Online ahead of print.
SARS-CoV-2 infection. Descriptive analysis of a selected case series
[Article in English, Spanish]
C L Errando[SUP] 1 [/SUP], C S Romero-García[SUP] 1 [/SUP], M J Hernández-Cádiz[SUP] 1 [/SUP], M Á Pallardó-López[SUP] 1 [/SUP], J Puig[SUP] 1 [/SUP]
Affiliations
- PMID: 34518043
- DOI: 10.1016/j.redar.2021.03.009
Abstract
Objectives: COVID-19 was declared pandemic by March 2020. Clinical, analytical, and radiological findings have been reported. Detailed different evolution of patients of the same local outbreak has been scarcely reported. We report 6 selected cases of such an evolution.
Clinical cases: The clinical, radiological, analytical evolution of 6patients is reported. Patients were selected as it were epidemiological close contacts, and showed particular different clinical evolution.
Results: The clinical course at the start of infection (first week) was similar among patients. In relationship with clinical evolution, middle to severe course were related with inflammation markers levels evolution (D-dimer, IL-6, ferritin, lymphocytes count, etc.). Specially lung alterations were observed, but neurological/neuropsychiatric findings are still common. In evolution, 2patients showed middle symptoms, but the 2most severely affected died.
Conclusions: It remains to be elucidated the different evolutive pathways and outcomes of COVD-19. In our 6patients of the same local outbreak, clinical, laboratory and radiological features were different. We discuss some aspects of the pathophysiology of the disease, other than the widely described of the respiratory system.
Keywords: Brote epidémico; COVID-19; Complicaciones; Complications; Coronavirus; ICU; Outbreak; UCI.