Reverse zoonosis of influenza to swine: new perspectives on the human-animal interface

[tetano]

Trends Microbiol. 2015 Jan 3. pii: S0966-842X(14)00246-7. doi: 10.1016/j.tim.2014.12.002. [Epub ahead of print]
[h=1]Reverse zoonosis of influenza to swine: new perspectives on the human-animal interface.[/h] Nelson MI[SUP]1[/SUP], Vincent AL[SUP]2[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] The origins of the 2009 influenza A (H1N1) pandemic in swine are unknown, highlighting gaps in our understanding of influenza A virus (IAV) ecology and evolution. We review how recently strengthened influenza virus surveillance in pigs has revealed that influenza virus transmission from humans to swine is far more frequent than swine-to-human zoonosis, and is central in seeding swine globally with new viral diversity. The scale of global human-to-swine transmission represents the largest 'reverse zoonosis' of a pathogen documented to date. Overcoming the bias towards perceiving swine as sources of human viruses, rather than recipients, is key to understanding how the bidirectional nature of the human-animal interface produces influenza threats to both hosts.
Published by Elsevier Ltd.


[h=4]KEYWORDS:[/h] evolution; human?animal interface; influenza A virus; pandemic; swine

PMID: 25564096 [PubMed - as supplied by publisher]


http://www.ncbi.nlm.nih.gov/pubmed/25564096

 

[Emily]

This seems a bellwether study. I couldn't access the full text but did listen to the video and it showed just how entrenched the one-way perspective is since even this video perpetuated the error made in pointing to civet cats as the source, or even intermediate host for SARs transmission from bats to humans.

http://researchnews.osu.edu/archive/SARStree.htm
http://www.medpagetoday.com/LabNotes/LabNotes/42676

That error led to unneeded culling of civets raised as food, who certainly did not have good lives or futures, but also led to even more tragic culling of pet dogs and cats in China. Truth seems to come out in little-noticed drips long after the damage done by a tidal wave of hubris and fear.