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Safety and efficacy of anti-influenza drugs, intravenous peramivir against influenza virus infection in elderly patients with underlying disease

tetano

Editor, Senior Moderator
J Microbiol Immunol Infect. 2017 Jun 26. pii: S1684-1182(17)30075-0. doi: 10.1016/j.jmii.2016.11.006. [Epub ahead of print]
[h=1]Safety and efficacy of anti-influenza drugs, intravenous peramivir against influenza virus infection in elderly patients with underlying disease.[/h] Takamatsu K[SUP]1[/SUP], Marumo S[SUP]2[/SUP], Fukui M[SUP]1[/SUP], Hata A[SUP]3[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] We retrospectively analyzed data of 38 elderly patients, each with an underlying disease, to evaluate peramivir safety and efficacy. Six patients (15.8%) experienced adverse events, all tolerated. Median time from administration until the return to normal temperatures was 31.5 h (95% CI: 22.4-40.6). Results confirm intravenous peramivir's usefulness.
Copyright ? 2017. Published by Elsevier B.V.


[h=4]KEYWORDS:[/h] Aging; Antiviral drugs; Geriatrics; Gerontology; High-risk patient; Neuraminidase inhibitor

PMID: 28720319 DOI: 10.1016/j.jmii.2016.11.006
 
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