tetano
Editor, Senior Moderator
SAGE Open Med Case Rep
. 2022 Jul 22;10:2050313X221113934.
doi: 10.1177/2050313X221113934. eCollection 2022.
COVID-19-induced latent relapsing hypercoagulable state in the absence of persistent viral infection
Adrija Hajra[SUP] 1 [/SUP], Juan Torrado[SUP] 1 [/SUP], Carlos L Alviar[SUP] 2 [/SUP], Sripal Bangalore[SUP] 2 [/SUP], Norma Keller[SUP] 2 [/SUP], Robert Faillace[SUP] 1 [/SUP], Seth Sokol[SUP] 3 [/SUP]
Affiliations
Abstract
Hypercoagulability in coronavirus disease 2019 infection is already a known fact. But in this article, we have discussed a unique case where the patient had suffered from relapsing thrombus formation. This report describes the case of a patient who presented with chronic coronavirus disease 2019-induced recurrent thrombi refractory to multiple antithrombotic regimens because of multiple recurrent inflammatory flares without any evidence of chronic persistent viral infection. The patient was treated with anticoagulation and anti-inflammatory medications. Still, he had repeated episodes of right ventricular thrombus. Coronavirus disease 2019 can provoke a severe relapsing hypercoagulable state without evidence of persisting viral infection. Rebound inflammatory flares rather than viral recurrence may play a trigger.
Keywords: COVID-19; anticoagulation; pulmonary embolism; right ventricular thrombus; thrombosis.
. 2022 Jul 22;10:2050313X221113934.
doi: 10.1177/2050313X221113934. eCollection 2022.
COVID-19-induced latent relapsing hypercoagulable state in the absence of persistent viral infection
Adrija Hajra[SUP] 1 [/SUP], Juan Torrado[SUP] 1 [/SUP], Carlos L Alviar[SUP] 2 [/SUP], Sripal Bangalore[SUP] 2 [/SUP], Norma Keller[SUP] 2 [/SUP], Robert Faillace[SUP] 1 [/SUP], Seth Sokol[SUP] 3 [/SUP]
Affiliations
- PMID: 35899245
- PMCID: PMC9310331
- DOI: 10.1177/2050313X221113934
Abstract
Hypercoagulability in coronavirus disease 2019 infection is already a known fact. But in this article, we have discussed a unique case where the patient had suffered from relapsing thrombus formation. This report describes the case of a patient who presented with chronic coronavirus disease 2019-induced recurrent thrombi refractory to multiple antithrombotic regimens because of multiple recurrent inflammatory flares without any evidence of chronic persistent viral infection. The patient was treated with anticoagulation and anti-inflammatory medications. Still, he had repeated episodes of right ventricular thrombus. Coronavirus disease 2019 can provoke a severe relapsing hypercoagulable state without evidence of persisting viral infection. Rebound inflammatory flares rather than viral recurrence may play a trigger.
Keywords: COVID-19; anticoagulation; pulmonary embolism; right ventricular thrombus; thrombosis.