tetano
Editor, Senior Moderator
Saudi Med J
. 2021 Oct;42(10):1083-1094.
doi: 10.15537/smj.2021.42.10.20210396.
Clinical and epidemiological characteristics of COVID-19 mortality in Saudi Arabia
Rawabi M Alsayer[SUP] 1 [/SUP], Hassan M Alsharif[SUP] 1 [/SUP], Abeer M Al Baadani[SUP] 1 [/SUP], Kiran A Kalam[SUP] 1 [/SUP]
Affiliations
Abstract
Objectives: To analyze the clinical and epidemiological characteristics for 224 of in-hospital coronavirus disease 2019 (COVID-19) mortality cases. This study's clinical implications provide insight into the significant death indicators among COVID-19 patients and the outbreak burden on the healthcare system in the Kingdom of Saudi Arabia (KSA).
Methods: A multi-center retrospective cross-sectional study conducted among all COVID-19 mortality cases admitted to 15 Armed Forces hospitals across KSA, from March to July 2020. Demographic data, clinical presentations, laboratory investigations, and complications of COVID-19 mortality cases were collected and analyzed.
Results: The mean age was 69.66±14.68 years, and 142 (63.4%) of the cases were male. Overall, 30% of the COVID-19 mortalities occurred in the first 24 hours of hospital admission, while 50% occurred on day 10. The most prevalent comorbidities were diabetes mellitus (DM, 73.7%), followed by hypertension (HTN, 69.6%). Logistic regression for risk factors in all mortality cases revealed that direct mortality cases from COVID-19 were more likely to develop acute respiratory distress syndrome (odds ratio [OR]: 1.75, confidence intervel [CI: 0.89-3.43]; p=0.102) and acute kidney injury (OR: 1.01, CI: [0.54-1.90]; p=0.960).
Conclusion: Aging, male gender and the high prevalence of the underlying diseases such as, DM and HTN were a significant death indicators among COVID-19 mortality cases in KSA. Increases in serum ferritin, procalcitonin, C-reactive protein (CRP), and D-dimer levels can be used as indicators of disease progression.
Keywords: COVID-19; Coronavirus; SARS-CoV-2; Saudi Arabia; epidemiology; mortality.
. 2021 Oct;42(10):1083-1094.
doi: 10.15537/smj.2021.42.10.20210396.
Clinical and epidemiological characteristics of COVID-19 mortality in Saudi Arabia
Rawabi M Alsayer[SUP] 1 [/SUP], Hassan M Alsharif[SUP] 1 [/SUP], Abeer M Al Baadani[SUP] 1 [/SUP], Kiran A Kalam[SUP] 1 [/SUP]
Affiliations
- PMID: 34611003
- DOI: 10.15537/smj.2021.42.10.20210396
Abstract
Objectives: To analyze the clinical and epidemiological characteristics for 224 of in-hospital coronavirus disease 2019 (COVID-19) mortality cases. This study's clinical implications provide insight into the significant death indicators among COVID-19 patients and the outbreak burden on the healthcare system in the Kingdom of Saudi Arabia (KSA).
Methods: A multi-center retrospective cross-sectional study conducted among all COVID-19 mortality cases admitted to 15 Armed Forces hospitals across KSA, from March to July 2020. Demographic data, clinical presentations, laboratory investigations, and complications of COVID-19 mortality cases were collected and analyzed.
Results: The mean age was 69.66±14.68 years, and 142 (63.4%) of the cases were male. Overall, 30% of the COVID-19 mortalities occurred in the first 24 hours of hospital admission, while 50% occurred on day 10. The most prevalent comorbidities were diabetes mellitus (DM, 73.7%), followed by hypertension (HTN, 69.6%). Logistic regression for risk factors in all mortality cases revealed that direct mortality cases from COVID-19 were more likely to develop acute respiratory distress syndrome (odds ratio [OR]: 1.75, confidence intervel [CI: 0.89-3.43]; p=0.102) and acute kidney injury (OR: 1.01, CI: [0.54-1.90]; p=0.960).
Conclusion: Aging, male gender and the high prevalence of the underlying diseases such as, DM and HTN were a significant death indicators among COVID-19 mortality cases in KSA. Increases in serum ferritin, procalcitonin, C-reactive protein (CRP), and D-dimer levels can be used as indicators of disease progression.
Keywords: COVID-19; Coronavirus; SARS-CoV-2; Saudi Arabia; epidemiology; mortality.