tetano
Editor, Senior Moderator
Sci Afr
. 2021 Aug 3;e00915.
doi: 10.1016/j.sciaf.2021.e00915. Online ahead of print.
New-Onset Type 1 Diabetes Mellitus with Diabetic Ketoacidosis and Pancreatitis in a Patient with COVID-19
Mostafa Alfishawy[SUP] 1 [/SUP], Mahmoud Nassar[SUP] 2 [/SUP], Mahmoud Mohamed[SUP] 3 [/SUP], Moataz Fatthy[SUP] 4 [/SUP], Riem El Messiery[SUP] 4 [/SUP]
Affiliations
Abstract
Coronavirus Disease 2019 (COVID-19) had struck the world with health and economic catastrophes and recently with unusual autoimmune presentations, including new-onset Type 1 Diabetes. Herein we present a 17-year-old male patient who presented to the Emergency room with fever, palpitation, and cough of four-week duration; he was referred to the Emergency room and was found to have DKA. CT of the chest showed ground-glass opacities suggestive of COVID-19 pneumonia, and abdominal cuts showed dilated intrahepatic biliary radicles with pancreatic loculations suggestive of pancreatitis. The patient was admitted to the ICU, started on Intravenous fluids and Insulin infusion then COVID-19 PCR returned positive. We hypothesize that SARS-CoV-2 has a vital role in eliciting an autoimmune response triggering Type 1 Diabetes, and further studies are needed to confirm this hypothesis. SARS-COV-2 may cause pancreatitis, and the first presentation could be high blood sugar or DKA.
Keywords: Covid-19; DKA; Diabetic Ketoacidosis; New-Onset; Pancreatitis; Type 1 Diabetes Mellitus.
. 2021 Aug 3;e00915.
doi: 10.1016/j.sciaf.2021.e00915. Online ahead of print.
New-Onset Type 1 Diabetes Mellitus with Diabetic Ketoacidosis and Pancreatitis in a Patient with COVID-19
Mostafa Alfishawy[SUP] 1 [/SUP], Mahmoud Nassar[SUP] 2 [/SUP], Mahmoud Mohamed[SUP] 3 [/SUP], Moataz Fatthy[SUP] 4 [/SUP], Riem El Messiery[SUP] 4 [/SUP]
Affiliations
- PMID: 34368517
- PMCID: PMC8329435
- DOI: 10.1016/j.sciaf.2021.e00915
Abstract
Coronavirus Disease 2019 (COVID-19) had struck the world with health and economic catastrophes and recently with unusual autoimmune presentations, including new-onset Type 1 Diabetes. Herein we present a 17-year-old male patient who presented to the Emergency room with fever, palpitation, and cough of four-week duration; he was referred to the Emergency room and was found to have DKA. CT of the chest showed ground-glass opacities suggestive of COVID-19 pneumonia, and abdominal cuts showed dilated intrahepatic biliary radicles with pancreatic loculations suggestive of pancreatitis. The patient was admitted to the ICU, started on Intravenous fluids and Insulin infusion then COVID-19 PCR returned positive. We hypothesize that SARS-CoV-2 has a vital role in eliciting an autoimmune response triggering Type 1 Diabetes, and further studies are needed to confirm this hypothesis. SARS-COV-2 may cause pancreatitis, and the first presentation could be high blood sugar or DKA.
Keywords: Covid-19; DKA; Diabetic Ketoacidosis; New-Onset; Pancreatitis; Type 1 Diabetes Mellitus.