tetano
Editor, Senior Moderator
Semin Respir Crit Care Med
. 2023 Feb;44(1):118-129.
doi: 10.1055/s-0042-1758837. Epub 2023 Jan 16.
Use of Antiviral Agents and other Therapies for COVID-19
Mark A T Blaskovich[SUP] 1 [/SUP], Anthony D Verderosa[SUP] 1 [/SUP]
Affiliations
Abstract
The coronavirus disease 2019 (COVID-19) pandemic led to a remarkably rapid development of a range of effective prophylactic vaccines, including new technologies that had not previously been approved for human use. In contrast, the development of new small molecule antiviral therapeutics has taken years to produce the first approved drugs specifically targeting severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), with the intervening years filled with attempts to repurpose existing drugs and the development of biological therapeutics. This review will discuss the reasons behind this variation in timescale and provide a survey of the many new treatments that are progressing through the clinical pipeline.
. 2023 Feb;44(1):118-129.
doi: 10.1055/s-0042-1758837. Epub 2023 Jan 16.
Use of Antiviral Agents and other Therapies for COVID-19
Mark A T Blaskovich[SUP] 1 [/SUP], Anthony D Verderosa[SUP] 1 [/SUP]
Affiliations
- PMID: 36646090
- DOI: 10.1055/s-0042-1758837
Abstract
The coronavirus disease 2019 (COVID-19) pandemic led to a remarkably rapid development of a range of effective prophylactic vaccines, including new technologies that had not previously been approved for human use. In contrast, the development of new small molecule antiviral therapeutics has taken years to produce the first approved drugs specifically targeting severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), with the intervening years filled with attempts to repurpose existing drugs and the development of biological therapeutics. This review will discuss the reasons behind this variation in timescale and provide a survey of the many new treatments that are progressing through the clinical pipeline.