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Severe Acute Respiratory Infection (SARI) surveillance for hospitalized patients in Northern Vietnam, 2011-2014

tetano

Editor, Senior Moderator
Jpn J Infect Dis. 2017 Mar 28. doi: 10.7883/yoken.JJID.2016.463. [Epub ahead of print]
[h=1]Severe Acute Respiratory Infection (SARI) surveillance for hospitalized patients in Northern Vietnam, 2011-2014.[/h] Nguyen HK[SUP]1[/SUP], Nguyen SV, Nguyen AP, Hoang PM, Le TT, Nguyen TC, Hoang HT, Vuong CD, Tran LT, Mai LQ.
[h=3]Author information[/h]

[h=3]Abstract[/h] Worldwide Severe Acute Respiratory Infections (SARI) are leading causes of hospitalization, morbidity and mortality in children. The aim of this study was to identify viral pathogens responsible for SARI in northern Vietnam from 2011 to 2014.
[h=4]METHODS:[/h] Throat swabs and tracheal aspirates were collected from SARI patients according to WHO Guidelines. Thirteen different viral pathogens (Influenza A(H1N)pdm09; A/H3N2; A/H5; A/H7 and B; Para influenza 1,2,3; RSV; HMPV; Adeno; SARS-CoV and Rhino) were tested by conventional/ real-time RT-PCR.
[h=4]RESULTS:[/h] During study period, 975 samples were collected and tested. More than thirty per cent (32.1%, 313 samples) showed evidence of infection with influenza viruses; contained A/H3N2 (48 samples), A(H1N1)pdm09 (221samples) , influenza B (42 samples) and co-infection of A(H1N1)pdm09 or A/H3N2 and influenza B (2 samples). Other respiratory pathogens were detected in 101samples as : Rhinovirus in 73 samples, Adenovirus (10 samples), hMPV (9 samples) , Parainfluenza 3(5 samples) , Parainfluenza 2 (3 samples), RSV (1 samples). No influenza A/H5, A /H7 or SARS-CoV were detected.
[h=4]CONCLUSION:[/h] Respiratory viral infection, particularly Influenza and Rhino viruses were associated with high rates of SARI hospitalized, and future studies correlating clinical aspects are needed to inform interventions including targeted vaccination.


PMID: 28367882 DOI: 10.7883/yoken.JJID.2016.463
 
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