tetano
Editor, Senior Moderator
Intern Med. 2012;51(12):1595-8. Epub 2012 Jun 15.
Simultaneous Development of Acute Disseminated Encephalomyelitis and Guillain-Barr? Syndrome Associated with H1N1 09 Influenza Vaccination.
Hoshino T, Uchiyama Y, Ito E, Osawa S, Ohashi T.
Source
Department of Neurology, Tokyo Women's Medical University, Japan.
Abstract
A 36-year-old man was admitted to our hospital because of urinary retention and muscle weakness affecting all 4 limbs after receiving a H1N1 09 influenza vaccination. Magnetic resonance imaging demonstrated multiple lesions in his brain and spinal cord. Furthermore, nerve conduction study showed acute sensorimotor neuropathy, and anti-GM2 antibodies were detected in his serum. Based on the temporal association and exclusion of alternative etiologies, we made a diagnosis of acute disseminated encephalomyelitis (ADEM) and Guillain-Barr? syndrome (GBS). To our knowledge, this is the first case of co-morbid ADEM and GBS after influenza vaccination with positive anti-ganglioside antibodies.
PMID:
22728497
[PubMed - in process]
Free full text
http://www.ncbi.nlm.nih.gov/pubmed/22728497
Simultaneous Development of Acute Disseminated Encephalomyelitis and Guillain-Barr? Syndrome Associated with H1N1 09 Influenza Vaccination.
Hoshino T, Uchiyama Y, Ito E, Osawa S, Ohashi T.
Source
Department of Neurology, Tokyo Women's Medical University, Japan.
Abstract
A 36-year-old man was admitted to our hospital because of urinary retention and muscle weakness affecting all 4 limbs after receiving a H1N1 09 influenza vaccination. Magnetic resonance imaging demonstrated multiple lesions in his brain and spinal cord. Furthermore, nerve conduction study showed acute sensorimotor neuropathy, and anti-GM2 antibodies were detected in his serum. Based on the temporal association and exclusion of alternative etiologies, we made a diagnosis of acute disseminated encephalomyelitis (ADEM) and Guillain-Barr? syndrome (GBS). To our knowledge, this is the first case of co-morbid ADEM and GBS after influenza vaccination with positive anti-ganglioside antibodies.
PMID:
22728497
[PubMed - in process]
Free full text
http://www.ncbi.nlm.nih.gov/pubmed/22728497