tetano
Editor, Senior Moderator
Influenza Other Respir Viruses. 2019 Nov 7. doi: 10.1111/irv.12700. [Epub ahead of print] [h=1]State-level estimates of excess hospitalizations and deaths associated with influenza.[/h]
Czaja CA[SUP]1,[/SUP][SUP]2,[/SUP][SUP]3[/SUP], Miller L[SUP]2[/SUP], Colborn K[SUP]2[/SUP], Cockburn MG[SUP]2[/SUP], Alden N[SUP]1[/SUP], Herlihy RK[SUP]1[/SUP], Sim?es EAF[SUP]2,[/SUP][SUP]3[/SUP].
[h=3]Author information[/h] 1 Colorado Department of Public Health and Environment, Denver, CO, USA. 2 Colorado School of Public Health, Aurora, CO, USA. 3 University of Colorado School of Medicine, Aurora, CO, USA.
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] National estimates of influenza burden may not reflect state-level influenza activity, and local surveillance may not capture the full burden of influenza.
[h=4]METHODS:[/h] To provide state-level information about influenza burden, we estimated excess pneumonia and influenza (P&I) and respiratory and circulatory (R&C) hospitalizations and deaths in Colorado from local hospital discharge records, death certificates, and influenza virus surveillance using negative binomial models.
[h=4]RESULTS:[/h] From July 2007 to June 2016, influenza was associated with an excess of 17 911 P&I hospitalizations (95%CI: 15 227, 20 354), 30 811 R&C hospitalizations (95%CI: 24 344, 37 176), 1,064 P&I deaths (95%CI: 757, 1298), and 3828 R&C deaths (95%CI: 2060, 5433). There was a large burden of influenza A(H1N1) among persons aged 0-64 years, with high median seasonal rates of excess hospitalization among persons aged 0-4 years. Persons aged ≥65 years experienced the largest numbers and highest median seasonal rates of excess hospitalization and death associated with influenza A (H3N2). The burden of influenza B was generally lower, with elevated median seasonal rates of excess hospitalization among persons aged 0-4 years and ≥65 years.
[h=4]CONCLUSIONS:[/h] These findings complement existing influenza surveillance. Periodic state-level estimates of influenza disease burden may be useful for setting state public health priorities and planning prevention and control initiatives.
? 2019 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.
[h=4]KEYWORDS:[/h] death; hospitalization; human; influenza; public health
PMID: 31702114 DOI: 10.1111/irv.12700
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Czaja CA[SUP]1,[/SUP][SUP]2,[/SUP][SUP]3[/SUP], Miller L[SUP]2[/SUP], Colborn K[SUP]2[/SUP], Cockburn MG[SUP]2[/SUP], Alden N[SUP]1[/SUP], Herlihy RK[SUP]1[/SUP], Sim?es EAF[SUP]2,[/SUP][SUP]3[/SUP].
[h=3]Author information[/h] 1 Colorado Department of Public Health and Environment, Denver, CO, USA. 2 Colorado School of Public Health, Aurora, CO, USA. 3 University of Colorado School of Medicine, Aurora, CO, USA.
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] National estimates of influenza burden may not reflect state-level influenza activity, and local surveillance may not capture the full burden of influenza.
[h=4]METHODS:[/h] To provide state-level information about influenza burden, we estimated excess pneumonia and influenza (P&I) and respiratory and circulatory (R&C) hospitalizations and deaths in Colorado from local hospital discharge records, death certificates, and influenza virus surveillance using negative binomial models.
[h=4]RESULTS:[/h] From July 2007 to June 2016, influenza was associated with an excess of 17 911 P&I hospitalizations (95%CI: 15 227, 20 354), 30 811 R&C hospitalizations (95%CI: 24 344, 37 176), 1,064 P&I deaths (95%CI: 757, 1298), and 3828 R&C deaths (95%CI: 2060, 5433). There was a large burden of influenza A(H1N1) among persons aged 0-64 years, with high median seasonal rates of excess hospitalization among persons aged 0-4 years. Persons aged ≥65 years experienced the largest numbers and highest median seasonal rates of excess hospitalization and death associated with influenza A (H3N2). The burden of influenza B was generally lower, with elevated median seasonal rates of excess hospitalization among persons aged 0-4 years and ≥65 years.
[h=4]CONCLUSIONS:[/h] These findings complement existing influenza surveillance. Periodic state-level estimates of influenza disease burden may be useful for setting state public health priorities and planning prevention and control initiatives.
? 2019 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.
[h=4]KEYWORDS:[/h] death; hospitalization; human; influenza; public health
PMID: 31702114 DOI: 10.1111/irv.12700
Free full text