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Editor, Senior Moderator
Source: http://7thspace.com/headlines/36729...uding_strong_interferon_alpha_production.html
Acute dengue virus 2 infection in Gabonese patients is associated with an early innate immune response, including strong interferon alpha production
Dengue is now a leading cause of morbidity and mortality throughout the tropics. We conducted the first ex vivo study of dengue fever (DF) in African patients infected during the first Gabonese dengue virus 2 (DENV-2) outbreak in 2007, in order to investigate cytokine production, including the antiviral cytokine IFN-alpha, reported to be a potent inhibitor of DENV replication in vitro...
... Conclusion: Acute DENV-2 infection in African patients elicits a strong innate response involving IFN-alpha production, as well as an adaptive immune response.
Author: Pierre BecquartNadia WauquierDieudonne NkogheAngelique Ndjoyi-MbiguinoCindy PadillaMarc SourisEric Leroy
Credits/Source: BMC Infectious Diseases 2010, 10:356
Acute dengue virus 2 infection in Gabonese patients is associated with an early innate immune response, including strong interferon alpha production
Dengue is now a leading cause of morbidity and mortality throughout the tropics. We conducted the first ex vivo study of dengue fever (DF) in African patients infected during the first Gabonese dengue virus 2 (DENV-2) outbreak in 2007, in order to investigate cytokine production, including the antiviral cytokine IFN-alpha, reported to be a potent inhibitor of DENV replication in vitro...
... Conclusion: Acute DENV-2 infection in African patients elicits a strong innate response involving IFN-alpha production, as well as an adaptive immune response.
Author: Pierre BecquartNadia WauquierDieudonne NkogheAngelique Ndjoyi-MbiguinoCindy PadillaMarc SourisEric Leroy
Credits/Source: BMC Infectious Diseases 2010, 10:356