Shiloh
Editor, Senior Moderator
Source: http://7thspace.com/headlines/43093...tiology_and_co_detection_as_risk_factors.html
Severe lower respiratory tract infection in infants and toddlers from a non-affluent population: viral etiology and co-detection as risk factors
Lower respiratory tract infection (LRTI) is a major cause of pediatric morbidity and mortality, especially among non-affluent communities. In this study we determine the impact of respiratory viruses and how viral co-detections/infections can affect clinical LRTI severity in children in a hospital setting.
Methods: Patients younger than 3 years of age admitted to a tertiary hospital in Brazil during the months of high prevalence of respiratory viruses had samples collected from nasopharyngeal aspiration...
Conclusions: Although RSV remains as the main cause of LRTI in infants our study indicates an increase in the length of hospital stay and oxygen use in infants with HRV detected by RT-PCR compared to those without HRV. Moreover, one can speculate that when HRV is detected simultaneously with RSV there is an additive effect that may be reflected in more severe clinical outcome.
Also, our study identified a significant number of children infected by recently identified viruses, such as hMPV and Human Bocavirus (HBov), and this is a novel finding for poor communities from developing countries.
Author: Emerson Rodrigues da SilvaPaulo Márcio PitrezEurico ArrudaRita MattielloEdgar E SarriaFlávia Escremim de PaulaJosé Luis Proença-ModenaLuana Sella DelcaroOtávio CintraMarcus H JonesJosé Dirceu RibeiroRenato T Stein
Credits/Source: BMC Infe
Published on: 2013-01-25
Severe lower respiratory tract infection in infants and toddlers from a non-affluent population: viral etiology and co-detection as risk factors
Lower respiratory tract infection (LRTI) is a major cause of pediatric morbidity and mortality, especially among non-affluent communities. In this study we determine the impact of respiratory viruses and how viral co-detections/infections can affect clinical LRTI severity in children in a hospital setting.
Methods: Patients younger than 3 years of age admitted to a tertiary hospital in Brazil during the months of high prevalence of respiratory viruses had samples collected from nasopharyngeal aspiration...
Conclusions: Although RSV remains as the main cause of LRTI in infants our study indicates an increase in the length of hospital stay and oxygen use in infants with HRV detected by RT-PCR compared to those without HRV. Moreover, one can speculate that when HRV is detected simultaneously with RSV there is an additive effect that may be reflected in more severe clinical outcome.
Also, our study identified a significant number of children infected by recently identified viruses, such as hMPV and Human Bocavirus (HBov), and this is a novel finding for poor communities from developing countries.
Author: Emerson Rodrigues da SilvaPaulo Márcio PitrezEurico ArrudaRita MattielloEdgar E SarriaFlávia Escremim de PaulaJosé Luis Proença-ModenaLuana Sella DelcaroOtávio CintraMarcus H JonesJosé Dirceu RibeiroRenato T Stein
Credits/Source: BMC Infe
Published on: 2013-01-25