Summary of status of development and availability of avian influenza A(H7N9) candidate vaccine viruses (WHO, September 26 2013)

[Giuseppe]

[Source: World Health Organization, full PDF document: (LINK). Edited.]


Summary of status of development and availability of avian influenza A(H7N9) candidate vaccine viruses

26 September 2013


Parent virus - Candidate vaccine virus - Type of virus or reassortant - Developing institute - Available from

• A/Shanghai/2/2013 Synthetic HA&NA
  • IDCDC-RG32A* - Reverse genetics - CDC, USA - CDC, USA
  • NIBRG-267* - Reverse genetics - NIBSC, UK - NIBSC, UK
  • CBER-RG4A* - Reverse genetics - CBER, USA - CBER, USA
• A/Anhui/1/2013
  • Wild type virus - WHO CCs
  • NIBRG-268* - Reverse genetics - NIBSC, UK - NIBSC, UK
  • NIIDRG-10.1* - Reverse genetics - NIID, Japan - NIID, Japan
  • IDCDC-RG33A** - Reverse genetics - CDC, USA - CDC, USA

* These viruses are candidate vaccine viruses which have passed relevant safety testing and two-way haemagglutination inhibition (HI) tests. They can be handled under BSL-2 enhanced containment(1).

** This is a potential candidate vaccine virus which has passed two-way haemagglutination inhibition (HI) tests but the safety testing is still being finalized. It must be handled under BSL-3 containment.
____

Institutes contact details for candidate vaccine viruses orders/information:

• CBER: Zhiping.Ye@fda.hhs.gov
• CDC: rvd6@cdc.gov
• NIBSC: standards@nibsc.org
• NIID: nobusawa@nih.go.jp
• WHO CCs: http://www.who.int/influenza/gisrs_laboratory/collaborating_centres/list/en/

Sheep antisera

[Antisera directed against: - Order Lot # - Available from]

• *A/Anhui/1/2013-like
  • 13/180 - 13/166# - NIBSC, UK

# Anti NA serum for tests of Neuraminidase identification

*new reference antisera
_____

The above-listed potency testing reagents for A(H7N9) vaccines have been developed with support from WHO CCs and Essential Regulatory Laboratories (ERLs) and calibrated by the ERLs that provide advice to WHO as part of the influenza vaccine virus selection and development process.

ERLs contact details for reagent orders and other information:

• NIBSC: standards@nibsc.org

For general enquiries, please contact gisrs-whohq@who.int

For other candidate vaccine viruses and potency testing reagents, please go to http://www.who.int/influenza/vaccines/virus/candidates_reagents/home/


-
-------