tetano
Editor, Senior Moderator
Rev Soc Bras Med Trop. 2012 Oct;45(5):563-6.
Surveillance of influenza A H1N1 2009 among school children during 2009 and 2010 in S?o Paulo, Brazil.
Guatura SB, Watanabe AS, Camargo CN, Passos AM, Parmezan SN, Tomazella TK, Carraro E, Kamikawa J, Granato C, Bellei N.
Source
Laborat?rio de Virologia Cl?nica, Departamento de Medicina, Universidade Federal de S?o Paulo, S?o Paulo, SP.
Abstract
INTRODUCTION:
Influenza A H1N1 2009 is associated with a high morbidity rate among children around the world, including Brazil. This survey was conducted on samples of symptomatic children (< 12 years) to investigate the influenza virus as the etiological agent of respiratory infections in a day care school in a health facility during the first and second pandemic wave of H1N1 (2009-2010) in S?o Paulo, Brazil.
METHODS:
Influenza infections were determined by real-time PCR in 34% (47/137) of children with a median age of 5 years (8 months - 12 years), from June to October 2009 and in 16% (14/85) of those with median age of 6 years (1-12 years), from March to November 2010.
RESULTS:
In general, most positive cases (64%) occurred in children aged 5-12 years, this age group was significantly the most affected (39.8%, p = 0.001, OR = 8.3, CI 95% 1.9-36.9). Wheezing was reported by 31% (19/61) and dyspnea by 23% (14/61) of the studied patients. An outbreak of influenza H1N1 with an attack rate of 35.7% among children (median age 6 years) was documented in April 2010, before the vaccination campaign against the pandemic virus was extended for children up to 5 years in Brazil.
CONCLUSIONS:
Therefore, the study reinforces the recommendation to immunize school children to reduce the incidence of the disease.
PMID:
23152337
[PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/23152337
Surveillance of influenza A H1N1 2009 among school children during 2009 and 2010 in S?o Paulo, Brazil.
Guatura SB, Watanabe AS, Camargo CN, Passos AM, Parmezan SN, Tomazella TK, Carraro E, Kamikawa J, Granato C, Bellei N.
Source
Laborat?rio de Virologia Cl?nica, Departamento de Medicina, Universidade Federal de S?o Paulo, S?o Paulo, SP.
Abstract
INTRODUCTION:
Influenza A H1N1 2009 is associated with a high morbidity rate among children around the world, including Brazil. This survey was conducted on samples of symptomatic children (< 12 years) to investigate the influenza virus as the etiological agent of respiratory infections in a day care school in a health facility during the first and second pandemic wave of H1N1 (2009-2010) in S?o Paulo, Brazil.
METHODS:
Influenza infections were determined by real-time PCR in 34% (47/137) of children with a median age of 5 years (8 months - 12 years), from June to October 2009 and in 16% (14/85) of those with median age of 6 years (1-12 years), from March to November 2010.
RESULTS:
In general, most positive cases (64%) occurred in children aged 5-12 years, this age group was significantly the most affected (39.8%, p = 0.001, OR = 8.3, CI 95% 1.9-36.9). Wheezing was reported by 31% (19/61) and dyspnea by 23% (14/61) of the studied patients. An outbreak of influenza H1N1 with an attack rate of 35.7% among children (median age 6 years) was documented in April 2010, before the vaccination campaign against the pandemic virus was extended for children up to 5 years in Brazil.
CONCLUSIONS:
Therefore, the study reinforces the recommendation to immunize school children to reduce the incidence of the disease.
PMID:
23152337
[PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/23152337