tetano
Editor, Senior Moderator
Emerg Infect Dis. 2019 Oct 17;25(10). doi: 10.3201/eid2510.190607. [Epub ahead of print]
[h=1]Susceptibility of Influenza A, B, C, and D Viruses to Baloxavir[SUP]1[/SUP].[/h] Mishin VP, Patel MC, Chesnokov A, De La Cruz J, Nguyen HT, Lollis L, Hodges E, Jang Y, Barnes J, Uyeki T, Davis CT, Wentworth DE, Gubareva LV.
[h=3]Abstract[/h] Baloxavir showed broad-spectrum in vitro replication inhibition of 4 types of influenza viruses (90% effective concentration range 1.2-98.3 nmol/L); susceptibility pattern was influenza A ˃ B ˃ C ˃ D. This drug also inhibited influenza A viruses of avian and swine origin, including viruses that have pandemic potential and those resistant to neuraminidase inhibitors.
[h=4]KEYWORDS:[/h] H7N9; United States; avian influenza; baloxavir; baloxavir marboxil; drug susceptibility; highly pathogenic viruses; influenza viruses; pandemic potential; respiratory infections; viruses; zoonoses; zoonotic influenza
PMID: 31287050 DOI: 10.3201/eid2510.190607
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[h=1]Susceptibility of Influenza A, B, C, and D Viruses to Baloxavir[SUP]1[/SUP].[/h] Mishin VP, Patel MC, Chesnokov A, De La Cruz J, Nguyen HT, Lollis L, Hodges E, Jang Y, Barnes J, Uyeki T, Davis CT, Wentworth DE, Gubareva LV.
[h=3]Abstract[/h] Baloxavir showed broad-spectrum in vitro replication inhibition of 4 types of influenza viruses (90% effective concentration range 1.2-98.3 nmol/L); susceptibility pattern was influenza A ˃ B ˃ C ˃ D. This drug also inhibited influenza A viruses of avian and swine origin, including viruses that have pandemic potential and those resistant to neuraminidase inhibitors.
[h=4]KEYWORDS:[/h] H7N9; United States; avian influenza; baloxavir; baloxavir marboxil; drug susceptibility; highly pathogenic viruses; influenza viruses; pandemic potential; respiratory infections; viruses; zoonoses; zoonotic influenza
PMID: 31287050 DOI: 10.3201/eid2510.190607
Free full text