tetano
Editor, Senior Moderator
Biosens Bioelectron. 2012 Mar 3. [Epub ahead of print]
Target-size embracing dimension for sensitive detection of viruses with various sizes and influenza virus strains.
Lin YY, Liao JD, Yang ML, Wu CL.
Source
Department of Materials Science and Engineering, National Cheng Kung University, 1 University Road, Tainan 70101, Taiwan.
Abstract
The focused ion beam (FIB) technique was employed to precisely fabricate hexagon-like Au nano-rods (fibAu_h) arrays as a surface enhanced Raman scattering - active substrate. A "ring diameter" (D(R)) was created by the convergence of three fibAu_h with respect to the dimension of the target viruses (D(T)), such as adenovirus (Adeno), encephalomyocarditis virus (EMCV), influenza virus (H1N1) with different sizes. Three influenza A virus strains were also compared. The results indicate that as that with a D(R)/D(T) ratio of around 1, the discrimination ability for detecting the target viruses and SERS mechanism become obvious. The enhanced lightning rod effect surrounding the seized target virus is anticipated if its size and dimension is suitably embraced within three fibAu_h. Hence the as-designed fibAu_h sample with a target-size embracing dimension provides good discrimination ability for distinguishing virus of various sizes or virus strains.
Copyright © 2012 Elsevier B.V. All rights reserved.
PMID:
22425238
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/22425238
Target-size embracing dimension for sensitive detection of viruses with various sizes and influenza virus strains.
Lin YY, Liao JD, Yang ML, Wu CL.
Source
Department of Materials Science and Engineering, National Cheng Kung University, 1 University Road, Tainan 70101, Taiwan.
Abstract
The focused ion beam (FIB) technique was employed to precisely fabricate hexagon-like Au nano-rods (fibAu_h) arrays as a surface enhanced Raman scattering - active substrate. A "ring diameter" (D(R)) was created by the convergence of three fibAu_h with respect to the dimension of the target viruses (D(T)), such as adenovirus (Adeno), encephalomyocarditis virus (EMCV), influenza virus (H1N1) with different sizes. Three influenza A virus strains were also compared. The results indicate that as that with a D(R)/D(T) ratio of around 1, the discrimination ability for detecting the target viruses and SERS mechanism become obvious. The enhanced lightning rod effect surrounding the seized target virus is anticipated if its size and dimension is suitably embraced within three fibAu_h. Hence the as-designed fibAu_h sample with a target-size embracing dimension provides good discrimination ability for distinguishing virus of various sizes or virus strains.
Copyright © 2012 Elsevier B.V. All rights reserved.
PMID:
22425238
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/22425238