tetano
Editor, Senior Moderator
J Crit Care. 2017 May 23;41:166-169. doi: 10.1016/j.jcrc.2017.05.014. [Epub ahead of print]
[h=1]The association between red cell distribution width and poor outcomes in hospitalized patients with influenza.[/h] Topaz G[SUP]1[/SUP], Kitay-Cohen Y[SUP]2[/SUP], Peled L[SUP]2[/SUP], Gharra W[SUP]2[/SUP], Kaminer K[SUP]2[/SUP], Eitan M[SUP]2[/SUP], Mahamid L[SUP]2[/SUP], Shilo L[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]PURPOSE:[/h] To examine an association between red blood cell distribution width (RDW) and the prognosis of influenza patients.
[h=4]METHODS:[/h] We conducted a retrospective analysis of patients hospitalized with influenza during 2012-2015 in the internal medicine wards of one medical center. RDW measurements during hospitalization were analyzed. Primary outcome was complicated hospitalization (defined as at least one of: length of stay ≥7days, need for mechanical ventilation, septic shock, transfer to intensive-care, or 30-day mortality). Secondary outcome was 30-day mortality.
[h=4]RESULTS:[/h] 153 patients were included, mean age: 62.5?1, 82 (54%) male; 84 (55%) had a high RDW value (>14.5%) during hospitalization. Patients with high and low RDW (≤14.5%) had similar age and comorbidity profiles, but those with high RDW had lower hemoglobin and higher creatinine levels. Patients with high RDW had a higher rate of complicated hospitalization (32.5% vs. 10.3%, p<0.01) and a trend for increased 30-day mortality. In a multivariate regression model, high RDW was a predictor of complicated hospitalization (OR 5.03, 95% CI 1.81-13.93, p<0.01). Each 1-point increase in RDW was associated with a 29% increase in the risk for the primary outcome.
[h=4]CONCLUSION:[/h] RDW>14.5% was a predictor of severe hospital complications in patients with influenza.
Copyright ? 2017 Elsevier Inc. All rights reserved.
[h=4]KEYWORDS:[/h] Hospital complications; Influenza; Mortality; Red cell distribution width
PMID: 28554095 DOI: 10.1016/j.jcrc.2017.05.014
[h=1]The association between red cell distribution width and poor outcomes in hospitalized patients with influenza.[/h] Topaz G[SUP]1[/SUP], Kitay-Cohen Y[SUP]2[/SUP], Peled L[SUP]2[/SUP], Gharra W[SUP]2[/SUP], Kaminer K[SUP]2[/SUP], Eitan M[SUP]2[/SUP], Mahamid L[SUP]2[/SUP], Shilo L[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]PURPOSE:[/h] To examine an association between red blood cell distribution width (RDW) and the prognosis of influenza patients.
[h=4]METHODS:[/h] We conducted a retrospective analysis of patients hospitalized with influenza during 2012-2015 in the internal medicine wards of one medical center. RDW measurements during hospitalization were analyzed. Primary outcome was complicated hospitalization (defined as at least one of: length of stay ≥7days, need for mechanical ventilation, septic shock, transfer to intensive-care, or 30-day mortality). Secondary outcome was 30-day mortality.
[h=4]RESULTS:[/h] 153 patients were included, mean age: 62.5?1, 82 (54%) male; 84 (55%) had a high RDW value (>14.5%) during hospitalization. Patients with high and low RDW (≤14.5%) had similar age and comorbidity profiles, but those with high RDW had lower hemoglobin and higher creatinine levels. Patients with high RDW had a higher rate of complicated hospitalization (32.5% vs. 10.3%, p<0.01) and a trend for increased 30-day mortality. In a multivariate regression model, high RDW was a predictor of complicated hospitalization (OR 5.03, 95% CI 1.81-13.93, p<0.01). Each 1-point increase in RDW was associated with a 29% increase in the risk for the primary outcome.
[h=4]CONCLUSION:[/h] RDW>14.5% was a predictor of severe hospital complications in patients with influenza.
Copyright ? 2017 Elsevier Inc. All rights reserved.
[h=4]KEYWORDS:[/h] Hospital complications; Influenza; Mortality; Red cell distribution width
PMID: 28554095 DOI: 10.1016/j.jcrc.2017.05.014