The Enigma ML FluAB-RSV assay: a fully automated molecular test for the rapid detection of influenza A, B and respiratory syncytial viruses in respira

[tetano]

Expert Rev Mol Diagn. 2014 Nov 17:1-10. [Epub ahead of print]
The Enigma ML FluAB-RSV assay: a fully automated molecular test for the rapid detection of influenza A, B and respiratory syncytial viruses in respiratory specimens.
Goldenberg SD1, Edgeworth JD.
Author information
Abstract

The Enigma? ML FluAB-RSV assay (Enigma Diagnostics, Porton Down, Salisbury, UK) is a CE-IVD marked multiplex molecular panel for the detection of influenza A, B and respiratory syncytial viruses in nasopharyngeal swabs. The assay runs on the fully automated Enigma ML platform without further specimen manipulation and provides a sample-to-answer result within 95 min. The reported sensitivity and specificity for influenza A are 100% (95% CI: 98.2-100) and 98.3% (95% CI: 95.5-99.4), respectively, for influenza B are 100% (95% CI: 98.2-100) and 98.7% (95% CI: 96-99.6), respectively, and for respiratory syncytial virus are 100% (95% CI: 98.2-100) and 99.4% (95% CI: 97.2-99.9), respectively.
KEYWORDS:

RSV; automation; influenza A; influenza B; multiplex PCR; point of care; rapid diagnosis; respiratory infection

PMID:
25399865
[PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/25399865