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The Intractable Puzzle of Sporadic Creutzfeldt-Jakob Disease in Very Young People

Emily

Editor, Senior Moderator
Author is from the MRC Prion Unit at UCL, Institute of Prion Diseases; and National Prion Clinic, University College London Hospitals NHS Foundation Trust, UK.

https://n.neurology.org/content/97/17/801

The Intractable Puzzle of Sporadic Creutzfeldt-Jakob Disease in Very Young People
Simon Mead
Neurology Oct 2021, 97 (17) 801-802; DOI: 10.1212/WNL.0000000000012739

In the era of randomized controlled trials and multicenter observational studies, it is easy for academic neurology to overlook the compelling questions posed by individual patient cases. Sporadic Creutzfeldt-Jakob disease (sCJD) in a 21-year-old patient was the right diagnosis, but hardly a satisfactory explanation for either the doctor or patient and his family in the Clinical/Scientific Note by Appleby et al.[SUP]1[/SUP] in this week's issue of Neurology®. How can a typically late-onset disorder occur in someone so young?
 
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