Giuseppe
Emeritus
[Source: The Lancet, full text: (LINK). Abstract, edited.]
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The Lancet, Early Online Publication, 18 October 2012
doi:10.1016/S0140-6736(12)61379-8
Global pattern of experienced and anticipated discrimination reported by people with major depressive disorder: a cross-sectional survey
Original Text
Dr Antonio Lasalvia MD a, Silvia Zoppei PsyD a, Tine Van Bortel PhD b, Chiara Bonetto PhD a, Doriana Cristofalo DrSciEdu a, Prof Kristian Wahlbeck MD c, Simon Vasseur Bacle d, Chantal Van Audenhove PhD e, Jaap van Weeghel PhD f, Blanca Reneses PhD g, Arunas Germanavicius PhD h, Marina Economou PhD i, Mariangela Lanfredi PsyD j, Shuntaro Ando MD b, Norman Sartorius MD k, Prof Juan J Lopez-Ibor PhD g, Prof Graham Thornicroft PhD b, the ASPEN/INDIGO Study Group?
Summary
Background
Depression is the third leading contributor to the worldwide burden of disease. We assessed the nature and severity of experienced and anticipated discrimination reported by adults with major depressive disorder worldwide. Moreover, we investigated whether experienced discrimination is related to clinical history, provision of health care, and disclosure of diagnosis and whether anticipated discrimination is associated with disclosure and previous experiences of discrimination.
Methods
In a cross-sectional survey, people with a diagnosis of major depressive disorder were interviewed in 39 sites (35 countries) worldwide with the discrimination and stigma scale (version 12; DISC-12). Other inclusion criteria were ability to understand and speak the main local language and age 18 years or older. The DISC-12 subscores assessed were reported discrimination and anticipated discrimination. Multivariable regression was used to analyse the data.
Findings
1082 people with depression completed the DISC-12. Of these, 855 (79%) reported experiencing discrimination in at least one life domain. 405 (37%) participants had stopped themselves from initiating a close personal relationship, 271 (25%) from applying for work, and 218 (20%) from applying for education or training. We noted that higher levels of experienced discrimination were associated with several lifetime depressive episodes (negative binomial regression coefficient 0?20 [95% CI 0?09?0?32], p=0?001); at least one lifetime psychiatric hospital admission (0?29 [0?15?0?42], p=0?001); poorer levels of social functioning (widowed, separated, or divorced 0?10 [0?01?0?19], p=0?032; unpaid employed 0?34 [0?09?0?60], p=0?007; looking for a job 0?26 [0?09?0?43], p=0?002; and unemployed 0?22 [0?03?0?41], p=0?022). Experienced discrimination was also associated with lower willingness to disclose a diagnosis of depression (mean discrimination score 4?18 [SD 3?68] for concealing depression vs 2?25 [2?65] for disclosing depression; p<0?0001). Anticipated discrimination is not necessarily associated with experienced discrimination because 147 (47%) of 316 participants who anticipated discrimination in finding or keeping a job and 160 (45%) of 353 in their intimate relationships had not experienced discrimination.
Interpretation
Discrimination related to depression acts as a barrier to social participation and successful vocational integration. Non-disclosure of depression is itself a further barrier to seeking help and to receiving effective treatment. This finding suggests that new and sustained approaches are needed to prevent stigmatisation of people with depression and reduce the effects of stigma when it is already established.
Funding
European Commission, Directorate General for Health and Consumers, Public Health Executive Agency.
a) Department of Public Health and Community Medicine, Section of Psychiatry, University of Verona, Verona, Italy; b) King's College London, Institute of Psychiatry, London, UK; c) National Institute for Health and Welfare, Helsinki, Vasa, Finland; d) Etablissement Public Sant? Mentale Lille-M?tropole, Armenti?res, France; e) Katholieke Universiteit Leuven, Leuven, Belgium; f) Stichting Kenniscentrum Phrenos, Utrecht, Netherlands; g) Instituto de Psiquiatria, Instituto de Investigaci?n Sanitaria del Hospital Cl?nico San Carlos, Centro para la Investigaci?n Biom?dica en Red en Salud Mental, Madrid, Spain; h) Vilnius University, Vilnius, Lithuania; i) University Mental Health Institute, Athens, Greece; j) Istituto di Ricovero e Cura a Carattere Scientifico Centro San Giovanni di Dio?Fatebenefratelli, Brescia, Italy; k) Association for the Improvement of Mental Health Programmes, Geneva, Switzerland
Correspondence to: Dr Antonio Lasalvia, Department of Public Health and Community Medicine, Section of Psychiatry, University of Verona, Policlinico ?G B Rossi?, P le Scuro, 10 37134, Verona, Italy
? Members listed at end of paper
-doi:10.1016/S0140-6736(12)61379-8
Global pattern of experienced and anticipated discrimination reported by people with major depressive disorder: a cross-sectional survey
Original Text
Dr Antonio Lasalvia MD a, Silvia Zoppei PsyD a, Tine Van Bortel PhD b, Chiara Bonetto PhD a, Doriana Cristofalo DrSciEdu a, Prof Kristian Wahlbeck MD c, Simon Vasseur Bacle d, Chantal Van Audenhove PhD e, Jaap van Weeghel PhD f, Blanca Reneses PhD g, Arunas Germanavicius PhD h, Marina Economou PhD i, Mariangela Lanfredi PsyD j, Shuntaro Ando MD b, Norman Sartorius MD k, Prof Juan J Lopez-Ibor PhD g, Prof Graham Thornicroft PhD b, the ASPEN/INDIGO Study Group?
Summary
Background
Depression is the third leading contributor to the worldwide burden of disease. We assessed the nature and severity of experienced and anticipated discrimination reported by adults with major depressive disorder worldwide. Moreover, we investigated whether experienced discrimination is related to clinical history, provision of health care, and disclosure of diagnosis and whether anticipated discrimination is associated with disclosure and previous experiences of discrimination.
Methods
In a cross-sectional survey, people with a diagnosis of major depressive disorder were interviewed in 39 sites (35 countries) worldwide with the discrimination and stigma scale (version 12; DISC-12). Other inclusion criteria were ability to understand and speak the main local language and age 18 years or older. The DISC-12 subscores assessed were reported discrimination and anticipated discrimination. Multivariable regression was used to analyse the data.
Findings
1082 people with depression completed the DISC-12. Of these, 855 (79%) reported experiencing discrimination in at least one life domain. 405 (37%) participants had stopped themselves from initiating a close personal relationship, 271 (25%) from applying for work, and 218 (20%) from applying for education or training. We noted that higher levels of experienced discrimination were associated with several lifetime depressive episodes (negative binomial regression coefficient 0?20 [95% CI 0?09?0?32], p=0?001); at least one lifetime psychiatric hospital admission (0?29 [0?15?0?42], p=0?001); poorer levels of social functioning (widowed, separated, or divorced 0?10 [0?01?0?19], p=0?032; unpaid employed 0?34 [0?09?0?60], p=0?007; looking for a job 0?26 [0?09?0?43], p=0?002; and unemployed 0?22 [0?03?0?41], p=0?022). Experienced discrimination was also associated with lower willingness to disclose a diagnosis of depression (mean discrimination score 4?18 [SD 3?68] for concealing depression vs 2?25 [2?65] for disclosing depression; p<0?0001). Anticipated discrimination is not necessarily associated with experienced discrimination because 147 (47%) of 316 participants who anticipated discrimination in finding or keeping a job and 160 (45%) of 353 in their intimate relationships had not experienced discrimination.
Interpretation
Discrimination related to depression acts as a barrier to social participation and successful vocational integration. Non-disclosure of depression is itself a further barrier to seeking help and to receiving effective treatment. This finding suggests that new and sustained approaches are needed to prevent stigmatisation of people with depression and reduce the effects of stigma when it is already established.
Funding
European Commission, Directorate General for Health and Consumers, Public Health Executive Agency.
a) Department of Public Health and Community Medicine, Section of Psychiatry, University of Verona, Verona, Italy; b) King's College London, Institute of Psychiatry, London, UK; c) National Institute for Health and Welfare, Helsinki, Vasa, Finland; d) Etablissement Public Sant? Mentale Lille-M?tropole, Armenti?res, France; e) Katholieke Universiteit Leuven, Leuven, Belgium; f) Stichting Kenniscentrum Phrenos, Utrecht, Netherlands; g) Instituto de Psiquiatria, Instituto de Investigaci?n Sanitaria del Hospital Cl?nico San Carlos, Centro para la Investigaci?n Biom?dica en Red en Salud Mental, Madrid, Spain; h) Vilnius University, Vilnius, Lithuania; i) University Mental Health Institute, Athens, Greece; j) Istituto di Ricovero e Cura a Carattere Scientifico Centro San Giovanni di Dio?Fatebenefratelli, Brescia, Italy; k) Association for the Improvement of Mental Health Programmes, Geneva, Switzerland
Correspondence to: Dr Antonio Lasalvia, Department of Public Health and Community Medicine, Section of Psychiatry, University of Verona, Policlinico ?G B Rossi?, P le Scuro, 10 37134, Verona, Italy
? Members listed at end of paper
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