tetano
Editor, Senior Moderator
Infect Genet Evol. 2015 Apr 6. pii: S1567-1348(15)00126-4. doi: 10.1016/j.meegid.2015.04.001. [Epub ahead of print]
[h=1]The repeated introduction of the H3N2 virus from human to swine during 1979-1993 in China.[/h] Zhu W[SUP]1[/SUP], Yang S[SUP]1[/SUP], Dong L[SUP]1[/SUP], Yang L[SUP]1[/SUP], Tang J[SUP]1[/SUP], Zou X[SUP]1[/SUP], Chen T[SUP]1[/SUP], Yang J[SUP]1[/SUP], Shu Y[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Limited data are available regarding the swine influenza viruses (SIVs) that circulated in Mainland China prior to the 1990s. Eleven H3N2 virus strains were isolated from swine populations from 1979 to 1992. To determine the origin and tendency of these SIVs, the phylogenetic and antigenic properties of these viruses were analyzed based on the whole genome sequenced and the HI titrations with post-infection ferret antisera against influenza A (H3N2) virus isolates of swine and human origin. The results revealed that these 11 SIVs originated from humans and were not maintained in swine populations, indicating the interspecies transmission from humans to pigs occurred frequently and independently throughout these periods. However, human H3N2 viruses might not have the ability to circulate in pig herds.
Copyright ? 2015. Published by Elsevier B.V.
[h=4]KEYWORDS:[/h] Genetic analysis; Human H3N2 in swine; Influenza viruses
PMID: 25858119 [PubMed - as supplied by publisher]
[h=1]The repeated introduction of the H3N2 virus from human to swine during 1979-1993 in China.[/h] Zhu W[SUP]1[/SUP], Yang S[SUP]1[/SUP], Dong L[SUP]1[/SUP], Yang L[SUP]1[/SUP], Tang J[SUP]1[/SUP], Zou X[SUP]1[/SUP], Chen T[SUP]1[/SUP], Yang J[SUP]1[/SUP], Shu Y[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Limited data are available regarding the swine influenza viruses (SIVs) that circulated in Mainland China prior to the 1990s. Eleven H3N2 virus strains were isolated from swine populations from 1979 to 1992. To determine the origin and tendency of these SIVs, the phylogenetic and antigenic properties of these viruses were analyzed based on the whole genome sequenced and the HI titrations with post-infection ferret antisera against influenza A (H3N2) virus isolates of swine and human origin. The results revealed that these 11 SIVs originated from humans and were not maintained in swine populations, indicating the interspecies transmission from humans to pigs occurred frequently and independently throughout these periods. However, human H3N2 viruses might not have the ability to circulate in pig herds.
Copyright ? 2015. Published by Elsevier B.V.
[h=4]KEYWORDS:[/h] Genetic analysis; Human H3N2 in swine; Influenza viruses
PMID: 25858119 [PubMed - as supplied by publisher]