tetano
Editor, Senior Moderator
Ther Apher Dial
. 2022 Jan 6.
doi: 10.1111/1744-9987.13790. Online ahead of print.
The incidence of acute kidney injury and its association with mortality in patients diagnosed with COVID-19 followed-up in intensive care unit
Nergiz Bayrakci[SUP] 1 [/SUP], Gülsüm Özkan[SUP] 1 [/SUP], Murat Şakaci[SUP] 2 [/SUP], Samet Sedef[SUP] 3 [/SUP], İlknur Erdem[SUP] 4 [/SUP], Nazan Tuna[SUP] 4 [/SUP], Levent Cem Mutlu[SUP] 5 [/SUP], İlker Yildirim[SUP] 6 [/SUP], Nuri Kiraz[SUP] 7 [/SUP], Berna Erdal[SUP] 7 [/SUP], Ebru Gelgeç[SUP] 8 [/SUP], Ayşen Erer[SUP] 8 [/SUP], Ömürhan Saraç[SUP] 8 [/SUP], Ahmet Yavuz[SUP] 2 [/SUP], Uysal Dolap[SUP] 9 [/SUP], Uluğ Bey Hayri[SUP] 9 [/SUP], İnci Kocadelioğlu[SUP] 9 [/SUP], Emrah Batmaz[SUP] 9 [/SUP]
Affiliations
Abstract
Introduction: The kidneys are some of the most frequently affected organs during coronavirus disease-2019 (COVID-19). This multicenter study evaluated the incidence of and risk factors for AKI in COVID-19 patients followed-up in intensive care unit, and its association with mortality.
Methods: Three hundred twenty-eight patients diagnosed with COVID-19 and hospitalized in intensive care unit were included. Risk factors associated with AKI and mortality were evaluated.
Results: Eighty-eight patients (27.9%) were diagnosed with AKI. AKI was significantly associated with older age, higher baseline creatinine level, lower albumin level and coexistence of cardiovascular disease and chronic obstructive pulmonary disease. Mortality in the entire study group was significantly associated with AKI, older age, requirement of IMV, higher neutrophile level, lower lymphocyte and albumin levels.
Conclusion: AKI is frequently seen during the course of COVID-19 and is associated with high mortality. Identifying AKI-related risk factors appears essential in the management of COVID-19 patients. This article is protected by copyright. All rights reserved.
Keywords: Acute kidney injury; COVID-19; Intensive care unit; Mortality.
. 2022 Jan 6.
doi: 10.1111/1744-9987.13790. Online ahead of print.
The incidence of acute kidney injury and its association with mortality in patients diagnosed with COVID-19 followed-up in intensive care unit
Nergiz Bayrakci[SUP] 1 [/SUP], Gülsüm Özkan[SUP] 1 [/SUP], Murat Şakaci[SUP] 2 [/SUP], Samet Sedef[SUP] 3 [/SUP], İlknur Erdem[SUP] 4 [/SUP], Nazan Tuna[SUP] 4 [/SUP], Levent Cem Mutlu[SUP] 5 [/SUP], İlker Yildirim[SUP] 6 [/SUP], Nuri Kiraz[SUP] 7 [/SUP], Berna Erdal[SUP] 7 [/SUP], Ebru Gelgeç[SUP] 8 [/SUP], Ayşen Erer[SUP] 8 [/SUP], Ömürhan Saraç[SUP] 8 [/SUP], Ahmet Yavuz[SUP] 2 [/SUP], Uysal Dolap[SUP] 9 [/SUP], Uluğ Bey Hayri[SUP] 9 [/SUP], İnci Kocadelioğlu[SUP] 9 [/SUP], Emrah Batmaz[SUP] 9 [/SUP]
Affiliations
- PMID: 34990070
- DOI: 10.1111/1744-9987.13790
Abstract
Introduction: The kidneys are some of the most frequently affected organs during coronavirus disease-2019 (COVID-19). This multicenter study evaluated the incidence of and risk factors for AKI in COVID-19 patients followed-up in intensive care unit, and its association with mortality.
Methods: Three hundred twenty-eight patients diagnosed with COVID-19 and hospitalized in intensive care unit were included. Risk factors associated with AKI and mortality were evaluated.
Results: Eighty-eight patients (27.9%) were diagnosed with AKI. AKI was significantly associated with older age, higher baseline creatinine level, lower albumin level and coexistence of cardiovascular disease and chronic obstructive pulmonary disease. Mortality in the entire study group was significantly associated with AKI, older age, requirement of IMV, higher neutrophile level, lower lymphocyte and albumin levels.
Conclusion: AKI is frequently seen during the course of COVID-19 and is associated with high mortality. Identifying AKI-related risk factors appears essential in the management of COVID-19 patients. This article is protected by copyright. All rights reserved.
Keywords: Acute kidney injury; COVID-19; Intensive care unit; Mortality.