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Trans R Soc Trop Med Hyg . COVID-19 in patients with chronic kidney disease: a 2-year study of incidence and mortality in relation to the variants

tetano

Editor, Senior Moderator
Trans R Soc Trop Med Hyg


. 2023 Apr 12;trad019.
doi: 10.1093/trstmh/trad019. Online ahead of print.
COVID-19 in patients with chronic kidney disease: a 2-year study of incidence and mortality in relation to the variants of concern waves in Brazil


Nathalie Bonatti Franco Almeida[SUP] 1 2 [/SUP], Priscilla Soares Filgueiras[SUP] 1 3 [/SUP], Adelina Junia Lourenço[SUP] 4 [/SUP], Cecilia Maria Florencio Bicalho[SUP] 4 [/SUP], Camila Amormino Corsini[SUP] 1 [/SUP], Daniel Alvim Pena de Miranda[SUP] 1 [/SUP], Sarah Vieira Contin Gomes[SUP] 1 [/SUP], Raquel V R Vilela[SUP] 4 [/SUP], Rafaella Fortini Queiroz Grenfell[SUP] 1 2 3 [/SUP]



Affiliations

Abstract

Background: Chronic kidney disease (CKD) is a risk factor for severe coronavirus disease (COVID-19). In Brazil, the disease is the 10th highest cause of death. We evaluated the epidemiological impact of COVID-19 in CDK and non-CDK patients.
Methods: Positive patients for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from 2020 to 2022 were classified according to the severity of COVID-19 and the numbers of cases and deaths were correlated to each wave of SARS-CoV-2 variants in Brazil.
Results: We compared all variables, and our data show that CDK significantly increased the mortality rate among patients, especially before COVID-19 vaccination, in comparison with non-CKD patients.
Conclusions: CKD patients had a significantly increased mortality rate compared with non-CKD.

Keywords: COVID-19; COVID-19 vaccines; SARS-CoV-2; chronic kidney disease; mortality; variants of concern.
 
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