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Transient Splenial Lesion of the Corpus Callosum in H1N1 Influenza Virus-Associated Encephalitis/Encephalopathy

tetano

tetano

Editor, Senior Moderator
Intern Med. 2011;50(8):915-8. Epub 2011 Apr 15.
Transient Splenial Lesion of the Corpus Callosum in H1N1 Influenza Virus-Associated Encephalitis/Encephalopathy.

Ito S, Shima S, Ueda A, Kawamura N, Asakura K, Mutoh T.

Department of Neurology, Fujita Health University School of Medicine, Japan.
Abstract

A 26-year-old man was admitted to our hospital because of high fever, drowsiness, memory disturbance, and disorientation due to H1N1 influenza virus-associated encephalitis/encephalopathy. All of his symptoms rapidly improved following methylprednisolone pulse therapy. The diffusion-weighted image of brain magnetic resonance imaging (MRI) revealed a large transient hyperintense signal lesion on the central splenium of the corpus callosum. This MRI finding in conjunction with a complete clinical recovery has been previously observed in cases of clinically mild seasonal influenza-associated encephalitis/encephalopathy, and can be also a useful clue for the diagnosis of new type of influenza, H1N1 influenza virus infection complicated by encephalitis/encephalopathy.

PMID: 21498942 [PubMed - in process]Free Article

http://www.ncbi.nlm.nih.gov/pubmed/21498942
 
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