tetano
Editor, Senior Moderator
Transl Psychiatry
. 2020 Oct 19;10(1):355.
doi: 10.1038/s41398-020-01039-2.
A quantitative and qualitative study on the neuropsychiatric sequelae of acutely ill COVID-19 inpatients in isolation facilities
Fengyi Hao[SUP] 1 [/SUP], Wilson Tam[SUP] 2 [/SUP], Xiaoyu Hu[SUP] 3 [/SUP], Wanqiu Tan[SUP] 4 [/SUP], Li Jiang[SUP] 1 [/SUP], Xiaojiang Jiang[SUP] 1 [/SUP], Ling Zhang[SUP] 1 [/SUP], Xinling Zhao[SUP] 1 [/SUP], Yiran Zou[SUP] 1 [/SUP], Yirong Hu[SUP] 1 [/SUP], Xi Luo[SUP] 5 [/SUP], Roger S McIntyre[SUP] 6 [/SUP], Travis Quek[SUP] 7 [/SUP], Bach Xuan Tran[SUP] 8 9 [/SUP], Zhisong Zhang[SUP] 10 [/SUP], Hai Quang Pham[SUP] 11 12 [/SUP], Cyrus S H Ho[SUP] 13 14 [/SUP], Roger C M Ho[SUP] 7 15 [/SUP]
Affiliations
Abstract
This study examined the neuropsychiatric sequelae of acutely ill patients with coronavirus disease 2019 (COVID-19) infection who received treatment in hospital isolation wards during the COVID-19 pandemic. Ten COVID-19 patients who received treatment in various hospitals in Chongqing, China; 10 age- and gender-matched psychiatric patients; and 10 healthy control participants residing in the same city were recruited. All participants completed a survey that collected information on demographic data, physical symptoms in the past 14 days and psychological parameters. Face-to-face interviews with COVID-19 patients were also performed using semi-structured questions. Among the COVID-19 patients, 40% had abnormal findings on the chest computed topography scan, 20% had dysosmia, 10% had dysgeusia, and 80% had repeated positivity on COVID-19 reverse-transcription polymerase chain reaction testing. COVID-19 and psychiatric patients were significantly more worried about their health than healthy controls (p = 0.019). A greater proportion of COVID-19 patients experienced impulsivity (p = 0.016) and insomnia (p = 0.039) than psychiatric patients and healthy controls. COVID-19 patients reported a higher psychological impact of the outbreak than psychiatric patients and healthy controls, with half of them having clinically significant symptoms of posttraumatic stress disorder. COVID-19 and psychiatric patients had higher levels of depression, anxiety and stress than healthy controls. Three themes emerged from the interviews with COVID-19 patients: (i) The emotions experienced by patients after COVID-19 infection (i.e., shock, fear, despair, hope, and boredom); (ii) the external factors that affected patients' mood (i.e., discrimination, medical expenses, care by healthcare workers); and (iii) coping and self-help behavior (i.e., distraction, problem-solving and online support). The future direction in COVID-19 management involves the development of a holistic inpatient service to promote immune and psychological resilience.
. 2020 Oct 19;10(1):355.
doi: 10.1038/s41398-020-01039-2.
A quantitative and qualitative study on the neuropsychiatric sequelae of acutely ill COVID-19 inpatients in isolation facilities
Fengyi Hao[SUP] 1 [/SUP], Wilson Tam[SUP] 2 [/SUP], Xiaoyu Hu[SUP] 3 [/SUP], Wanqiu Tan[SUP] 4 [/SUP], Li Jiang[SUP] 1 [/SUP], Xiaojiang Jiang[SUP] 1 [/SUP], Ling Zhang[SUP] 1 [/SUP], Xinling Zhao[SUP] 1 [/SUP], Yiran Zou[SUP] 1 [/SUP], Yirong Hu[SUP] 1 [/SUP], Xi Luo[SUP] 5 [/SUP], Roger S McIntyre[SUP] 6 [/SUP], Travis Quek[SUP] 7 [/SUP], Bach Xuan Tran[SUP] 8 9 [/SUP], Zhisong Zhang[SUP] 10 [/SUP], Hai Quang Pham[SUP] 11 12 [/SUP], Cyrus S H Ho[SUP] 13 14 [/SUP], Roger C M Ho[SUP] 7 15 [/SUP]
Affiliations
- PMID: 33077738
- DOI: 10.1038/s41398-020-01039-2
Abstract
This study examined the neuropsychiatric sequelae of acutely ill patients with coronavirus disease 2019 (COVID-19) infection who received treatment in hospital isolation wards during the COVID-19 pandemic. Ten COVID-19 patients who received treatment in various hospitals in Chongqing, China; 10 age- and gender-matched psychiatric patients; and 10 healthy control participants residing in the same city were recruited. All participants completed a survey that collected information on demographic data, physical symptoms in the past 14 days and psychological parameters. Face-to-face interviews with COVID-19 patients were also performed using semi-structured questions. Among the COVID-19 patients, 40% had abnormal findings on the chest computed topography scan, 20% had dysosmia, 10% had dysgeusia, and 80% had repeated positivity on COVID-19 reverse-transcription polymerase chain reaction testing. COVID-19 and psychiatric patients were significantly more worried about their health than healthy controls (p = 0.019). A greater proportion of COVID-19 patients experienced impulsivity (p = 0.016) and insomnia (p = 0.039) than psychiatric patients and healthy controls. COVID-19 patients reported a higher psychological impact of the outbreak than psychiatric patients and healthy controls, with half of them having clinically significant symptoms of posttraumatic stress disorder. COVID-19 and psychiatric patients had higher levels of depression, anxiety and stress than healthy controls. Three themes emerged from the interviews with COVID-19 patients: (i) The emotions experienced by patients after COVID-19 infection (i.e., shock, fear, despair, hope, and boredom); (ii) the external factors that affected patients' mood (i.e., discrimination, medical expenses, care by healthcare workers); and (iii) coping and self-help behavior (i.e., distraction, problem-solving and online support). The future direction in COVID-19 management involves the development of a holistic inpatient service to promote immune and psychological resilience.