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Transplant Proc . Post-Covid-19 Cholangiopathy-A New Indication for Liver Transplantation: A Case Report

tetano

Editor, Senior Moderator
Transplant Proc


. 2021 Mar 12;S0041-1345(21)00150-0.
doi: 10.1016/j.transproceed.2021.03.007. Online ahead of print.
Post-Covid-19 Cholangiopathy-A New Indication for Liver Transplantation: A Case Report


Francisco A Durazo[SUP] 1 [/SUP], Allyssa A Nicholas[SUP] 2 [/SUP], Jennifer J Mahaffey[SUP] 2 [/SUP], Shannon Sova[SUP] 3 [/SUP], John J Evans[SUP] 4 [/SUP], Juan Pablo Trivella[SUP] 5 [/SUP], Veronica Loy[SUP] 5 [/SUP], Joohyun Kim[SUP] 2 [/SUP], Michael A Zimmerman[SUP] 2 [/SUP], Johnny C Hong[SUP] 6 [/SUP]



Affiliations

Abstract

Liver injury is one of the nonpulmonary manifestations described in coronavirus disease 2019 (COVID-19). Post-COVID-19 cholangiopathy is a special entity of liver injury that has been suggested as a variant of secondary sclerosing cholangitis in critically ill patients (SSC-CIP). In the general population, the outcome of SSC-CIP has been reported to be poor without orthotopic liver transplantation (OLT). However, the role of OLT for post-COVID-19 cholangiopathy is unknown. We present a case report of a 47-year-old man who recovered from acute respiratory distress syndrome from COVID-19 and subsequently developed end-stage liver disease from post-COVID-19 cholangiopathy. The patient underwent OLT and is doing well with normal liver tests for 7 months. To our knowledge, this is the first case report of a patient who underwent successful liver transplantation for post-COVID-19 cholangiopathy.
 
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