tetano
Editor, Senior Moderator
Transplant Proc
. 2021 Nov 12;S0041-1345(21)00794-6.
doi: 10.1016/j.transproceed.2021.11.002. Online ahead of print.
Vaccine-Induced Thrombotic Thrombocytopenia Due to Coronavirus Disease 2019 Vaccine From a Deceased Donor: A Case Report
Swarnalatha Guditi[SUP] 1 [/SUP], Girish Setty[SUP] 2 [/SUP], Manish Verma[SUP] 2 [/SUP], Ram Reddy[SUP] 3 [/SUP], Rahul Devraj[SUP] 3 [/SUP], Sree Bhushan Raju[SUP] 4 [/SUP], Gopal Krishna Gokhale[SUP] 2 [/SUP]
Affiliations
Abstract
With the rapid and massive vaccination campaign against coronavirus disease 2019 (COVID-19) taking place across the globe, there are increasing reports of thrombotic complications with various COVID-19 vaccines such as the Pfizer-BioNTech mRNA, Moderna mRNA, AstraZeneca Oxford (serum institute), and Johnson & Johnson/Janssen vaccines. We report a case of successful organ donation from an 18-year-old woman who presented with cerebral venous thrombosis caused by vaccine-induced thrombotic thrombocytopenia following the first dose of the COVID-19 vaccine (AstraZeneca, University of Oxford, and Serum Institute of India), which caused brain death. Four recipients received 5 organs, kidneys (2), liver (1), and combined heart and lung (1). All 4 recipients had normal graft function without any thrombotic complications after 16 weeks of transplantation. This is first such case being reported from Asian countries.
. 2021 Nov 12;S0041-1345(21)00794-6.
doi: 10.1016/j.transproceed.2021.11.002. Online ahead of print.
Vaccine-Induced Thrombotic Thrombocytopenia Due to Coronavirus Disease 2019 Vaccine From a Deceased Donor: A Case Report
Swarnalatha Guditi[SUP] 1 [/SUP], Girish Setty[SUP] 2 [/SUP], Manish Verma[SUP] 2 [/SUP], Ram Reddy[SUP] 3 [/SUP], Rahul Devraj[SUP] 3 [/SUP], Sree Bhushan Raju[SUP] 4 [/SUP], Gopal Krishna Gokhale[SUP] 2 [/SUP]
Affiliations
- PMID: 34916063
- DOI: 10.1016/j.transproceed.2021.11.002
Abstract
With the rapid and massive vaccination campaign against coronavirus disease 2019 (COVID-19) taking place across the globe, there are increasing reports of thrombotic complications with various COVID-19 vaccines such as the Pfizer-BioNTech mRNA, Moderna mRNA, AstraZeneca Oxford (serum institute), and Johnson & Johnson/Janssen vaccines. We report a case of successful organ donation from an 18-year-old woman who presented with cerebral venous thrombosis caused by vaccine-induced thrombotic thrombocytopenia following the first dose of the COVID-19 vaccine (AstraZeneca, University of Oxford, and Serum Institute of India), which caused brain death. Four recipients received 5 organs, kidneys (2), liver (1), and combined heart and lung (1). All 4 recipients had normal graft function without any thrombotic complications after 16 weeks of transplantation. This is first such case being reported from Asian countries.