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Travel Med Infect Dis . Cost-effectiveness analysis of seasonal influenza vaccination during pregnancy: A systematic review

tetano

Editor, Senior Moderator
Travel Med Infect Dis


. 2023 Aug 15;102632.
doi: 10.1016/j.tmaid.2023.102632. Online ahead of print. Cost-effectiveness analysis of seasonal influenza vaccination during pregnancy: A systematic review

Zakieh Ostad-Ahmadi[SUP] 1 [/SUP], Sara Boccalini[SUP] 2 [/SUP], Amin Daemi[SUP] 3 [/SUP], Alireza Mahboub-Ahari[SUP] 4 [/SUP]



Affiliations
Abstract

Background: Seasonal influenza vaccination is clinically important and reduces hospitalization costs for pregnant women. However, is it also a cost-effective intervention?
Method: We conducted a systematic search of Medline (via PUBMED), EMBASE, SCOPUS, and Web of Science databases. We included any economic evaluation studies that reported Incremental Cost-Effectiveness Ratios for vaccinating pregnant women against influenza.
Result: Out of 927 potentially eligible articles, only 14 full texts met our inclusion criteria. In almost all studies, vaccinating pregnant women was a cost-effective and cost-saving strategy. In one study, it was not cost-effective when the researchers used costs and probabilities related to other groups (healthy adults) due to the lack of data for pregnant women. The main factors influencing the cost-effectiveness of the studies were vaccine efficacy and vaccination cost.
Conclusion: Influenza vaccination of pregnant women is a cost-effective intervention. More studies on the cost-effectiveness of this intervention in underdeveloped countries are needed.

Keywords: cost-benefit; cost-effectiveness; cost-utility; influenza vaccine; pregnancy; women economic evaluation..

 
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