tetano
Editor, Senior Moderator
Travel Med Infect Dis
. 2020 Aug 2;101830.
doi: 10.1016/j.tmaid.2020.101830. Online ahead of print.
SARS-CoV-2 jumping the species barrier: zoonotic lessons from SARS, MERS and recent advances to combat this pandemic virus
Kuldeep Dhama[SUP] 1 [/SUP], Shailesh Kumar Patel[SUP] 2 [/SUP], Khan Sharun[SUP] 3 [/SUP], Mamta Pathak[SUP] 2 [/SUP], Ruchi Tiwari[SUP] 4 [/SUP], Mohd Iqbal Yatoo[SUP] 5 [/SUP], Yashpal Singh Malik[SUP] 6 [/SUP], Ranjit Sah[SUP] 7 [/SUP], Ali A Rabaan[SUP] 8 [/SUP], Parmod Kumar Panwar[SUP] 9 [/SUP], Karam Pal Singh[SUP] 2 [/SUP], Izabela Michalak[SUP] 10 [/SUP], Wanpen Chaicumpa[SUP] 11 [/SUP], Dayron F Martinez-Pulgarin[SUP] 12 [/SUP], D Katterine Bonilla-Aldana[SUP] 13 [/SUP], Alfonso J Rodriguez-Morales[SUP] 14 [/SUP]
Affiliations
Abstract
Coronavirus Disease 2019 (COVID-19), caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome - Coronavirus-2) of the family Coronaviridae, appeared in China in December 2019. This disease was declared as posing Public Health International Emergency by World Health Organization on January 30, 2020, attained the status of a very high-risk category on February 29, and now having a pandemic status (March 11). COVID-19 has presently spread to more than 215 countries/territories while killing nearly 0.62 million humans out of cumulative confirmed infected asymptomatic or symptomatic cases accounting to almost 15 million as of July 22, 2020, within a short period of just a few months. Researchers worldwide are pacing with high efforts to counter the spread of this virus and to design effective vaccines and therapeutics/drugs. Few of the studies have shown the potential of the animal-human interface and zoonotic links in the origin of SARS-CoV-2. Exploring the possible zoonosis and revealing the factors responsible for its initial transmission from animals to humans will pave ways to design and implement effective preventive and control strategies to counter the COVID-19. The present review presents a comprehensive overview of COVID-19 and SARS-CoV-2, with emphasis on the role of animals and their jumping the cross-species barriers, experiences learned from SARS- and MERS-CoVs, zoonotic links, and spillover events, transmission to humans and rapid spread, and highlights the new advances in diagnosis, vaccine and therapies, preventive and control measures, one health concept along with recent research developments to counter this pandemic disease.
Keywords: COVID-19; SARS-Cov-2; bat coronavirus; control; diagnosis; expanding host range; one health; prevention; spillover; zoonosis.
. 2020 Aug 2;101830.
doi: 10.1016/j.tmaid.2020.101830. Online ahead of print.
SARS-CoV-2 jumping the species barrier: zoonotic lessons from SARS, MERS and recent advances to combat this pandemic virus
Kuldeep Dhama[SUP] 1 [/SUP], Shailesh Kumar Patel[SUP] 2 [/SUP], Khan Sharun[SUP] 3 [/SUP], Mamta Pathak[SUP] 2 [/SUP], Ruchi Tiwari[SUP] 4 [/SUP], Mohd Iqbal Yatoo[SUP] 5 [/SUP], Yashpal Singh Malik[SUP] 6 [/SUP], Ranjit Sah[SUP] 7 [/SUP], Ali A Rabaan[SUP] 8 [/SUP], Parmod Kumar Panwar[SUP] 9 [/SUP], Karam Pal Singh[SUP] 2 [/SUP], Izabela Michalak[SUP] 10 [/SUP], Wanpen Chaicumpa[SUP] 11 [/SUP], Dayron F Martinez-Pulgarin[SUP] 12 [/SUP], D Katterine Bonilla-Aldana[SUP] 13 [/SUP], Alfonso J Rodriguez-Morales[SUP] 14 [/SUP]
Affiliations
- PMID: 32755673
- DOI: 10.1016/j.tmaid.2020.101830
Abstract
Coronavirus Disease 2019 (COVID-19), caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome - Coronavirus-2) of the family Coronaviridae, appeared in China in December 2019. This disease was declared as posing Public Health International Emergency by World Health Organization on January 30, 2020, attained the status of a very high-risk category on February 29, and now having a pandemic status (March 11). COVID-19 has presently spread to more than 215 countries/territories while killing nearly 0.62 million humans out of cumulative confirmed infected asymptomatic or symptomatic cases accounting to almost 15 million as of July 22, 2020, within a short period of just a few months. Researchers worldwide are pacing with high efforts to counter the spread of this virus and to design effective vaccines and therapeutics/drugs. Few of the studies have shown the potential of the animal-human interface and zoonotic links in the origin of SARS-CoV-2. Exploring the possible zoonosis and revealing the factors responsible for its initial transmission from animals to humans will pave ways to design and implement effective preventive and control strategies to counter the COVID-19. The present review presents a comprehensive overview of COVID-19 and SARS-CoV-2, with emphasis on the role of animals and their jumping the cross-species barriers, experiences learned from SARS- and MERS-CoVs, zoonotic links, and spillover events, transmission to humans and rapid spread, and highlights the new advances in diagnosis, vaccine and therapies, preventive and control measures, one health concept along with recent research developments to counter this pandemic disease.
Keywords: COVID-19; SARS-Cov-2; bat coronavirus; control; diagnosis; expanding host range; one health; prevention; spillover; zoonosis.