tetano
Editor, Senior Moderator
Trop Med Health
. 2024 Sep 4;52(1):57.
doi: 10.1186/s41182-024-00617-0. A serological survey of COVID-19 among predominantly aboriginal residents of a tourist island in southern Thailand
Supakorn Sripaew[SUP] 1 2 [/SUP], Kameelah Yasharad[SUP] 3 [/SUP], Dzerlina S Rahari[SUP] 1 [/SUP], Weiyan Feng[SUP] 1 [/SUP], Zhenzhu Qian[SUP] 1 [/SUP], Huynh Ngoc Thanh[SUP] 1 [/SUP], Pei Li[SUP] 1 [/SUP], Agus Fitriangga[SUP] 1 [/SUP], Satiti Palupi Purwanto[SUP] 1 [/SUP], Aye Nyein Phyu[SUP] 1 [/SUP], Fangming Xianyu[SUP] 1 [/SUP], Sombat Phadungvitvatthana[SUP] 4 [/SUP], Wit Wichaidit[SUP] 1 [/SUP], Ponlagrit Kumwichar[SUP] 1 [/SUP], Virasakdi Chongsuvivatwong[SUP] 5 [/SUP]
Affiliations
Background: The current survey describes the seroprevalence, history of coronavirus disease 2019 (COVID-19), and vaccination status among predominantly aboriginal residents on a tourist island in southern Thailand. This information can be translated into COVID-19 vaccination and control plans for this population.
Methods: We implemented questionnaire interviews and collected blood samples from 249 residents of Lipe Island, Satun Province, in January 2022. We measured the anti-nucleocapsid protein and anti-spike (anti-S) receptor-binding protein levels of immunoglobulin (Ig) M and IgG. The differences in antibody levels among participants with different histories of vaccination and infection were analyzed using one-way analysis of variance with multiple comparisons.
Results: During the 2-year pandemic period, no island residents with COVID-19 required hospitalization despite the high prevalence of hypertension (33.3%) and diabetes mellitus (21.7%). Approximately 18.8% of the participants reported a history of COVID-19 diagnosis. In total, 95.1% of the participants had a history of complete vaccination, of which 93.5% were seropositive. The anti-S IgG geometric means (geometric standard deviation) were 3945.8 (2.0), 829.8 (9.7) AU/mL, 789.9 (5.3) AU/mL, and 22.7 (7.1) AU/mL, respectively, in participants with a history of both COVID-19 diagnosis and complete vaccination (group 1), incomplete vaccination and subsequent COVID-19 diagnosis (group 2), complete vaccination but no previous infection (group 3), or neither previous COVID-19 and complete vaccination (group 4). Significant pairwise differences in anti-S IgG levels were found between certain groups (1 vs 3, 1 vs 4, 2 vs 4, and 3 vs 4).
Conclusions: The high coverage of vaccination, high levels of population antibody titers, variable antibody levels among completely vaccinated non-infected residents, and high prevalence of non-communicable diseases (NCDs) suggested that the local health systems could control the pandemic. However, continuing surveillance, booster vaccinations, and NCD prevention programs were still required.
Keywords: COVID-19; Chronic disease; Ethnicity; Seroprevalence; Tourism.
. 2024 Sep 4;52(1):57.
doi: 10.1186/s41182-024-00617-0. A serological survey of COVID-19 among predominantly aboriginal residents of a tourist island in southern Thailand
Supakorn Sripaew[SUP] 1 2 [/SUP], Kameelah Yasharad[SUP] 3 [/SUP], Dzerlina S Rahari[SUP] 1 [/SUP], Weiyan Feng[SUP] 1 [/SUP], Zhenzhu Qian[SUP] 1 [/SUP], Huynh Ngoc Thanh[SUP] 1 [/SUP], Pei Li[SUP] 1 [/SUP], Agus Fitriangga[SUP] 1 [/SUP], Satiti Palupi Purwanto[SUP] 1 [/SUP], Aye Nyein Phyu[SUP] 1 [/SUP], Fangming Xianyu[SUP] 1 [/SUP], Sombat Phadungvitvatthana[SUP] 4 [/SUP], Wit Wichaidit[SUP] 1 [/SUP], Ponlagrit Kumwichar[SUP] 1 [/SUP], Virasakdi Chongsuvivatwong[SUP] 5 [/SUP]
Affiliations
- PMID: 39232844
- DOI: 10.1186/s41182-024-00617-0
Background: The current survey describes the seroprevalence, history of coronavirus disease 2019 (COVID-19), and vaccination status among predominantly aboriginal residents on a tourist island in southern Thailand. This information can be translated into COVID-19 vaccination and control plans for this population.
Methods: We implemented questionnaire interviews and collected blood samples from 249 residents of Lipe Island, Satun Province, in January 2022. We measured the anti-nucleocapsid protein and anti-spike (anti-S) receptor-binding protein levels of immunoglobulin (Ig) M and IgG. The differences in antibody levels among participants with different histories of vaccination and infection were analyzed using one-way analysis of variance with multiple comparisons.
Results: During the 2-year pandemic period, no island residents with COVID-19 required hospitalization despite the high prevalence of hypertension (33.3%) and diabetes mellitus (21.7%). Approximately 18.8% of the participants reported a history of COVID-19 diagnosis. In total, 95.1% of the participants had a history of complete vaccination, of which 93.5% were seropositive. The anti-S IgG geometric means (geometric standard deviation) were 3945.8 (2.0), 829.8 (9.7) AU/mL, 789.9 (5.3) AU/mL, and 22.7 (7.1) AU/mL, respectively, in participants with a history of both COVID-19 diagnosis and complete vaccination (group 1), incomplete vaccination and subsequent COVID-19 diagnosis (group 2), complete vaccination but no previous infection (group 3), or neither previous COVID-19 and complete vaccination (group 4). Significant pairwise differences in anti-S IgG levels were found between certain groups (1 vs 3, 1 vs 4, 2 vs 4, and 3 vs 4).
Conclusions: The high coverage of vaccination, high levels of population antibody titers, variable antibody levels among completely vaccinated non-infected residents, and high prevalence of non-communicable diseases (NCDs) suggested that the local health systems could control the pandemic. However, continuing surveillance, booster vaccinations, and NCD prevention programs were still required.
Keywords: COVID-19; Chronic disease; Ethnicity; Seroprevalence; Tourism.