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Type 3 hypersensitivity in COVID-19 vasculitis

Emily

Emily

Editor, Senior Moderator
https://www.sciencedirect.com/science/article/pii/S1521661620304526
Type 3 hypersensitivity in COVID-19 vasculitis
Author: Luca Roncati,Giulia Ligabue,Luca Fabbiani,Claudia Malagoli,Graziana Gallo,Beatrice Lusenti,Vincenzo Nasillo,Antonio Manenti,Antonio Maiorana
Publication: Clinical Immunology
Publisher:Elsevier
Date:August 2020

Highlights

•COVID-19 is an ongoing public health emergency around the world.
•New knowledge about its immunopathogenic mechanisms is required.
•Type 3 hypersensitivity reaction in COVID-19 vasculitis is here disclosed.
•Inflamed vascular smooth muscle cells concur to the cytokine storm via IL-6.
•Histology, histochemistry and immunofluorescence have been successfully applied.
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