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U.K. FMD outbreak possibly caused by faulty vaccine

Treyfish

Moderator
FOOT & MOUTH DISEASE, BOVINE - UK (02): 01 BFS67-LIKE VIRUS

Date: 4 Aug 2007
Source: Department for Environment, Food and Rural Affairs [edited]
<http://www.defra.gov.uk/news/latest/2007/animal-0803.htm>


Foot and mouth disease confirmed in cattle, in Surrey
The foot and mouth disease (FMD) strain found in Surrey is not one
currently known to be recently found in animals. It is most similar
to strains used in international diagnostic laboratories and in
vaccine production
, including at the Pirbright site shared by the
Institute of Animal Health (IAH) and Merial Animal Health Ltd, a
pharmaceutical company. The present indications are that this strain
is a 01 BFS67-like virus, isolated in the 1967 Foot and Mouth Disease
outbreak in Great Britain.


This strain is present at the IAH and was used in a batch
manufactured in July 2007 by the Merial facility
. On a precautionary
basis Merial has agreed to voluntarily halt vaccine production.


In response to this new information Debby Reynolds, chief veterinary
officer, has instructed that a new single protection zone be created
encompassing both the infected farm premises and the Pirbright site,
with a single 10-km [6.2-mile] radius surveillance zone.

Immediate action is being taken with an investigation led by the
health and safety executive at the Institute for Animal Health and Merial.

In addition an urgent independent review into biosecurity
arrangements at both sites has been commissioned led by Professor
Brian Spratt of Imperial University. It will report to Hilary Benn
and Debby Reynolds.

This incident remains at an early stage. It is too soon to reach any
firm conclusions. All potential sources of the virus will continue to
be investigated. All other precautionary measures announced yesterday
[3 Aug 2007] remain in place.

--
Communicated by:
ProMED-mail Rapporteur Mary Marshall
[Similar material communicated by: Andrea Jones, Charlie Calisher
(former ProMED-mail Viral Diseases Moderator), and John Morgan]

[This must be a live-virus strain that is being used to develop the
vaccine. It causes one to wonder how the vaccine strain found itself
outside of the research area. Certainly there are many speculations
that one can imagine, but presently there are not answers.
This
incident seems to be a deja vu experience for Mod.MHJ.- Mod.TG]:tiphat:
http://www.promedmail.org/pls/prome..._BACK_PAGE,F2400_P1001_PUB_MAIL_ID:1000,38680
 
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