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Uttar Pradesh Outbreaks - Possible mutated H1N1?

Ronan Kelly

Retired 2020
Samples have not tested positive for H1N1, but the CMO seems to suggest that this is because of a mutation. There also seems to be concurrent outbreaks of malaria, dengue and typhoid, but the feeling I get from this report is that the mysterious fever which is killing hundreds may be flu.




1 ... New incarnation of the Diocese of health flu sick Oct 20, 10:22 pm कानपुर, मुख्य संवाददाता: शहर नहीं, पूरा सूबा इस समय बुखार की भयावहता से जूझ रहा है। Kanpur, Chief Correspondent: city not currently meet the province is grappling with the magnitude of fever. लेकिन स्वास्थ्य विभाग के अफसर इसे विचित्र बुखार बताकर पल्ला झाड़ रहे हैं। But health department officials are tree skirt by letting it strange fever. चिकित्सकीय पड़ताल में चला है कि विचित्र बुखार जैसा कुछ नहीं है, सही बात यह है कि स्वाइन फ्लू नया रूप धरकर सता रहा है। Clinical investigations have shown that the fever There is nothing strange, true thing that is troubling Dharkara new swine flu. इंडियन चेस्ट सोसायटी ने इस गंभीर स्थिति पर शासन को आगाह कर अपनी वार्षिक आम सभा में बीमारी के विविध प्रभावों पर विशेष चर्चा कराने का फैसला किया है। Indian Chest Society warn of the dire situation ruled diverse effects of the disease in its annual general meeting decided to hold special discussion. बुखार नहीं, स्वास्थ्य विभाग विचित्र No fever, health department bizarre नगर, देहात (रमाबाई नगर) व आसपास के जनपदों में 700 से ज्यादा जानें ले चुका बुखार स्वास्थ्य विभाग प्रशासन की नाक में दम किये हैं। City, Countryside (Ramabai Nagar) and the surrounding districts have taken in more than 700 Learn fever plaguing the health department of the administration have. महज, रमाबाई नगर में अब तक 333 लोगों की बुखार से मौत हो चुकी है। Only, Ramabai Nagar far 333 people have died from fever. नगर में भी आंकड़ा सौ पार कर चुका है। The figure has exceeded one hundred in the city. इसके बावजूद स्वास्थ्य विभाग के अधिकारी बताने की स्थिति में नहीं है कि यह बुखार कौन सा है? Nevertheless, Health Department officials are not in a position to state that this fever is? मुख्य चिकित्साधिकारी डॉ.अशोक मिश्रा का कहना है कि वायरल, टाइफाइड, डेंगू के मिले जुले लक्षणों वाले मरीज आ रहे हैं। Chief Medical Officer Dr Ashok Mishra said that viral, typhoid, dengue patients with mixed symptoms are coming. कुछ मरीजों में लक्षणों के आधार पर स्वाइन फ्लू की संभावना के तहत उनका एच1एन1 परीक्षण कराया गया किंतु परिणाम नकारात्मक आया। Flu symptoms in some patients based on their H 1 N 1 under likely trial was conducted but the results came negative.
इंडियन चेस्ट सोसायटी गंभीर Indian Chest Society severe
इंडियन चेस्ट सोसायटी ने नगर व आसपास के जिलों में बुखार से हो रही मौतों को गंभीरता से लिया है। Indian Chest Society, the city and surrounding districts fever deaths being taken seriously. अगले माह जोधपुर में होने वाली आम सभा व राष्ट्रीय सम्मेलन में इस मुद्दे पर विशेष चर्चा होगी। General Assembly next month to be held in Jodhpur and National Conference will focus specifically on the issue. तब तक अलग-अलग स्तरों पर विशेषज्ञों से स्वाइन फ्लू के इस नये रूप का आकलन कराकर संकलित रिपोर्ट शासन को सौंपी जाएगी। Until then, different - different levels of flu experts by making the new assessment as compiled report will be submitted to the rule. सोसायटी के राष्ट्रीय अध्यक्ष व गणेश शंकर विद्यार्थी स्मारक चिकित्सा महाविद्यालय के पूर्व चेस्ट विभागाध्यक्ष डॉ.एसके कटियार ने बताया इस समय बुखार के जो मरीज सामने आ रहे हैं, उनमें अधिकतर में स्वाइन फ्लू के लक्षण सामने आये हैं। Society's national president and Ganesh Shankar Memorial Medical College student, former head of the department Dr SK Katiyar said the chest while the patient are exposed to fever, flu symptoms in most of them have come before. स्वाइन फ्लू में जुकाम, बुखार, खांसी व बदन दर्द तो अन्य वायरल संक्रमण के शिकार मरीजों जैसा ही होता है, साथ ही पेट दर्द व सांस फूलने की समस्या भी होती है। Swine flu colds, fever, cough and body aches like the other patients is a victim of viral infections, as well as abdominal pain and breathing problem is to thrive.
---------------------- ----------------------

जांच में पुष्टि नहीं, बढ़ी समस्या Investigation confirmed, increased problem
स्वाइन फ्लू के लिए होने वाली एच1एन1 जांच नकारात्मक आने से चिकित्सकों को इलाज में दिक्कत आ रही है। Swine flu to check the H 1 N 1 negative coming difficulty in coming to physicians treating. उनका कहना है कि एक ही कोशिका में इन्फ्लुएंजा व एच1एन1 के अलग-अलग वायरस प्रवेश होते हैं तो उनके जीन भी बदल जाते हैं। He said the same cell in H 1 N 1 influenza and different - different viruses have entered the turn, their genes. मौजूदा दौर में स्वाइन फ्लू के वायरस में यही जेनेटिक बदलाव हुआ है। Current round of flu virus genetic variation that is. इसी से बुखार नये रूप में सामने आया है। This has emerged as the new fever.
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(इनसेट-1) (Inset 1)

ये हैं लक्षण These symptoms

*जुकाम * Cold

*बुखार Fever

*खांसी * Cough

*पेट दर्द * Abdominal pain

*बदन दर्द * Aches

*सांस फूलना * Shortness of breath

(इनसेट-2) (Inset 2)

'स्वाइन फ्लू व इनफ्लुएंजा का वायरस मिलकर हमला कर रहा है, इसीलिए रिपोर्ट भी पॉजिटिव नहीं आ रही है। "Influanza swine flu and the virus is attacking together, so the report is not positive. इस पर गंभीर शोध व विचार विमर्श की जरूरत है।' A serious research and discussion is needed. " -डॉ.एसके कटियार, अध्यक्ष, इंडियन चेस्ट सोसायटी - Dr. SK Katiyar, President, Indian Chest Society

(इनसेट-3) (Inset 3)

'बुखार तो बहुतायत में हैं। "Fever in the abundance. यह कई बुखारों का मिलाजुला रूप लग रहा है। It sounds as a mix of many Bukharoan. इसका वायरस नहीं पता चल पा रहा है। The virus is not being able to know. इस कारण अधिक दिक्कत हो रही है।' The reason is more trouble. " -डॉ.अशोक मिश्रा, मुख्य चिकित्सा अधिकारी, कानपुर नगर - Dr. Ashok Mishra, Chief Medical Officer, Kanpur Nagar

http://translate.googleusercontent....le.com&usg=ALkJrhg91HdhPcP-n91xj3Nujiy_Y9nyXQ
 
Re: Kanpur, Uttar Pradesh: Post-Monsoon disease outbreaks 2010 - 333 fatalities - Dengue, malaria, H1N1, others suspected

Re: Kanpur, Uttar Pradesh: Post-Monsoon disease outbreaks 2010 - 333 fatalities - Dengue, malaria, H1N1, others suspected

I am reading a hint that there is a suspicion of co-infections leading to a reassortant virus?

He said the same cell in H 1 N 1 influenza and different - different viruses have entered the turn, their genes. मौजूदा दौर में स्वाइन फ्लू के वायरस में यही जेनेटिक बदलाव हुआ है। Current round of flu virus genetic variation that is. इसी से बुखार नये रूप में सामने आया है। This has emerged as the new fever.

I hope that samples are being sent to TPTB internationally for genetic sequencing and a closer look.

There is also a possible suggestion that people who have had H1N1 previously are succumbing to this virus, or this could be interpreted as people suffering fever have exhibited flu like symptoms prior to fever onset.

Society's national president and Ganesh Shankar Memorial Medical College student, former head of the department Dr SK Katiyar said the chest while the patient are exposed to fever, flu symptoms in most of them have come before.
 
Re: Uttar Pradesh Outbreaks - Possible mutated H1N1?

These are the numbers of confirmed H1N1 cases and fatalities from Uttar Pradesh since August 1.

UP cases.webp

UP fatalities.webp

It can be seen that a post monsoon outbreak occurred peaking around Sep 5. In total, 283 cases and 20 fatalities were reported.

There is little doubt that these numbers are a gross underestimate. Consider the United States for example - from May 2009 to April 2010 around 320 pediatric flu fatalities were reported. But the CDC estimates that around 1,270 children actually died as a result of the pandemic. In other words, in a country where pediatric reporting is mandatory, where presumably each case had access to hospital care, only a quarter of the estimated fatalities were actually confirmed. One wonders what the ratio would be for rural Uttar Pradesh? 1:10? 1:20? If so, then the confirmed numbers may represent at a minimum 200+ fatalities for this H1N1 outbreak in Uttar Pradesh. In the US the cfr is estimated around 0.02% - even if the cfr in India were greater, say 0.05%, 200 fatalities would represent 400,000 infected individuals.

Alternatively, if 10% of the population became infected, we would expect 3,800 fatalities using the estimated cfr from the US.

As the outbreak peaked in the first half of September, people who are currently suffering from respiratory symptoms may be suffering from co-infections and may not be testing positive for H1N1. It is also possible that if nasal swabs are being tested, that any lingering deep lung infection is being missed. I do not believe that a mutation theory is necessary to account for negative tests at this stage.

Uttar Pradesh has a population of 190,000,000. One would expect 10's of thousands of flu deaths from the State each year. In India as a whole, a child dies each minute from pneumonia - 10,000 per week, and that's just the kids. While the current outbreak in Uttar Pradesh is of interest and bears watching for any continued increase in fatalities - I believe that it is explicable within the context of seasonal post-monsoon outbreaks.
 
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