tetano
Editor, Senior Moderator
Vaccine
. 2023 Jun 13;S0264-410X(23)00621-7.
doi: 10.1016/j.vaccine.2023.05.060. Online ahead of print. Patient influenza vaccination reduces the risk of hospital-acquired influenza: An incident test negative-case control study in Lyon university hospital, France (2004-2020)
Mitra Saadatian-Elahi[SUP] 1 [/SUP], Laetitia Henaff[SUP] 1 [/SUP], Christelle Elias[SUP] 1 [/SUP], Marta C Nunes[SUP] 2 [/SUP], Arnaud Hot[SUP] 3 [/SUP], Géraldine Martin-Gaujard[SUP] 4 [/SUP], Vanessa Escuret[SUP] 5 [/SUP], Selilah Amour[SUP] 1 [/SUP], Philippe Vanhems[SUP] 6 [/SUP]
Affiliations
Background: Literature is limited on the impact of patient vaccination on the risk of hospital-acquired influenza (HAI). This test negative case-control study nested in a surveillance program aimed at evaluating the effectiveness of influenza vaccination in reducing the risk of HAI in hospitalized patients during 15 influenza seasons (2004-05 to 2019-20).
Methods: HAI cases were those who developed influenza like illness (ILI) symptoms at least 72 h after hospitalization and had a positive reverse transcriptase-polymerase chain reaction (RT-PCR). Controls were those with ILI symptoms and a negative RT-PCR test. A nasal swab as well as socio-demographic, clinical data and information on influenza vaccination were collected.
Results: Of the 296 patients included, 67 were confirmed HAI cases. Influenza vaccine coverage was significantly higher among controls compared to HAI cases (p = 0.002). The risk of HAI was reduced by almost 60 % in vaccinated patients.
Conclusions: A better control of HAI can be achieved by vaccinating hospitalized patients.
Keywords: France; Hospital-acquired; Influenza; Surveillance; Vaccine.
. 2023 Jun 13;S0264-410X(23)00621-7.
doi: 10.1016/j.vaccine.2023.05.060. Online ahead of print. Patient influenza vaccination reduces the risk of hospital-acquired influenza: An incident test negative-case control study in Lyon university hospital, France (2004-2020)
Mitra Saadatian-Elahi[SUP] 1 [/SUP], Laetitia Henaff[SUP] 1 [/SUP], Christelle Elias[SUP] 1 [/SUP], Marta C Nunes[SUP] 2 [/SUP], Arnaud Hot[SUP] 3 [/SUP], Géraldine Martin-Gaujard[SUP] 4 [/SUP], Vanessa Escuret[SUP] 5 [/SUP], Selilah Amour[SUP] 1 [/SUP], Philippe Vanhems[SUP] 6 [/SUP]
Affiliations
- PMID: 37321894
- DOI: 10.1016/j.vaccine.2023.05.060
Background: Literature is limited on the impact of patient vaccination on the risk of hospital-acquired influenza (HAI). This test negative case-control study nested in a surveillance program aimed at evaluating the effectiveness of influenza vaccination in reducing the risk of HAI in hospitalized patients during 15 influenza seasons (2004-05 to 2019-20).
Methods: HAI cases were those who developed influenza like illness (ILI) symptoms at least 72 h after hospitalization and had a positive reverse transcriptase-polymerase chain reaction (RT-PCR). Controls were those with ILI symptoms and a negative RT-PCR test. A nasal swab as well as socio-demographic, clinical data and information on influenza vaccination were collected.
Results: Of the 296 patients included, 67 were confirmed HAI cases. Influenza vaccine coverage was significantly higher among controls compared to HAI cases (p = 0.002). The risk of HAI was reduced by almost 60 % in vaccinated patients.
Conclusions: A better control of HAI can be achieved by vaccinating hospitalized patients.
Keywords: France; Hospital-acquired; Influenza; Surveillance; Vaccine.