tetano
Editor, Senior Moderator
Vector Borne Zoonotic Dis
. 2022 Apr 6.
doi: 10.1089/vbz.2022.0003. Online ahead of print.
SARS-CoV-2 Seroprevalence in Children from Western Romania, March to June 2021
Tudor Rares Olariu[SUP] 1 2 3 [/SUP], Alina Cristiana Craciun[SUP] 2 [/SUP], Daliborca Cristina Vlad[SUP] 4 5 [/SUP], Victor Dumitrascu[SUP] 4 5 [/SUP], Liviu Laurentiu Pop[SUP] 6 7 [/SUP], Florin Horhat[SUP] 8 9 [/SUP], Maria Alina Lupu[SUP] 1 3 10 [/SUP]
Affiliations
Abstract
Limited data are available regarding severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence in children. In this study, we assessed for the first time the seroprevalence of SARS-CoV-2 in children from Romania. Serum samples of 379 children were investigated for the presence of SARS-CoV-2 total antibodies. Serologic tests were performed using Elecsys Anti-SARS-CoV-2 electrochemiluminiscence immunoassay that targets the nucleocapsid protein of the virus. The overall seroprevalence of SARS-CoV-2 total antibodies was 46.70%. No significant difference was observed between seropositive and seronegative children according to age groups, gender, and area of residence. Our findings revealed a high SARS-CoV-2 seroprevalence in Romanian children at the end of the third COVID-19 pandemic wave. Results suggest that children, regardless of age, gender, or area of residence, are susceptible to infection with SARS-CoV-2. Seroprevalence in children was similar to the seroprevalence reported in the adult population from Western Romania during the same period of time, March to June 2021.
Keywords: COVID-19; Romania; SARS-CoV-2; children; epidemiology; seroprevalence.
. 2022 Apr 6.
doi: 10.1089/vbz.2022.0003. Online ahead of print.
SARS-CoV-2 Seroprevalence in Children from Western Romania, March to June 2021
Tudor Rares Olariu[SUP] 1 2 3 [/SUP], Alina Cristiana Craciun[SUP] 2 [/SUP], Daliborca Cristina Vlad[SUP] 4 5 [/SUP], Victor Dumitrascu[SUP] 4 5 [/SUP], Liviu Laurentiu Pop[SUP] 6 7 [/SUP], Florin Horhat[SUP] 8 9 [/SUP], Maria Alina Lupu[SUP] 1 3 10 [/SUP]
Affiliations
- PMID: 35384727
- DOI: 10.1089/vbz.2022.0003
Abstract
Limited data are available regarding severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence in children. In this study, we assessed for the first time the seroprevalence of SARS-CoV-2 in children from Romania. Serum samples of 379 children were investigated for the presence of SARS-CoV-2 total antibodies. Serologic tests were performed using Elecsys Anti-SARS-CoV-2 electrochemiluminiscence immunoassay that targets the nucleocapsid protein of the virus. The overall seroprevalence of SARS-CoV-2 total antibodies was 46.70%. No significant difference was observed between seropositive and seronegative children according to age groups, gender, and area of residence. Our findings revealed a high SARS-CoV-2 seroprevalence in Romanian children at the end of the third COVID-19 pandemic wave. Results suggest that children, regardless of age, gender, or area of residence, are susceptible to infection with SARS-CoV-2. Seroprevalence in children was similar to the seroprevalence reported in the adult population from Western Romania during the same period of time, March to June 2021.
Keywords: COVID-19; Romania; SARS-CoV-2; children; epidemiology; seroprevalence.