tetano
Editor, Senior Moderator
Vet World
. 2021 Oct;14(10):2817-2826.
doi: 10.14202/vetworld.2021.2817-2826. Epub 2021 Oct 30.
Reverse zoonosis of coronavirus disease-19: Present status and the control by one health approach
R Kumar Pramod[SUP] 1 [/SUP], Asha V Nair[SUP] 2 [/SUP], Padmakar Kamalakar Tambare[SUP] 1 [/SUP], Kanchana Chauhan[SUP] 1 [/SUP], T Vinay Kumar[SUP] 1 [/SUP], R Anju Rajan[SUP] 3 [/SUP], Blessy M Mani[SUP] 4 [/SUP], Muhasin Asaf[SUP] 5 [/SUP], Amit Kumar Pandey[SUP] 1 6 [/SUP]
Affiliations
Abstract
The recent coronavirus disease (COVID-19) outbreak is one of its kind in the history of public health that has created a major global threat. The causative agent, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a zoonotic source and hence, reverse zoonosis (disease transmission from humans to animals) increases the risk and rate of SARS-CoV-2 infection. Serological and molecular analyses and experimental infection studies have identified SARS-CoV-2 infection in several animal species in various countries. Different domestic and wild animals, including cats, dogs, tigers, lions, puma, snow leopard, minks, and pet ferrets, are infected naturally with SARS-CoV-2, mostly through suspected human to animal transmission. In addition, in vivo experimental inoculation studies have reported the susceptibility of cats, ferrets, hamsters, Egyptian fruit bats, and non-human primates to the virus. These experimentally infected species are found to be capable of virus transmission to co-housed animals of the same species. However, SARS-CoV-2 showed poor replication in livestock species such as pigs, chickens, and ducks with no detection of viral RNA after the animals were deliberately inoculated with the virus or exposed to the infected animals. As the pets/companion animals are more susceptible to COVID-19, the infection in animals needs an in-depth and careful study to avoid any future transmissions. The one health approach is the best inter-disciplinary method to understand the consequences of viral spread and prevention in novel host populations for the betterment of public health. Further in this review, we will explain in detail the different natural and experimentally induced cases of human to animal SARS-CoV-2 infection.
Keywords: mink; non-human primate; one health; reverse zoonosis; severe acute respiratory syndrome coronavirus 2.
. 2021 Oct;14(10):2817-2826.
doi: 10.14202/vetworld.2021.2817-2826. Epub 2021 Oct 30.
Reverse zoonosis of coronavirus disease-19: Present status and the control by one health approach
R Kumar Pramod[SUP] 1 [/SUP], Asha V Nair[SUP] 2 [/SUP], Padmakar Kamalakar Tambare[SUP] 1 [/SUP], Kanchana Chauhan[SUP] 1 [/SUP], T Vinay Kumar[SUP] 1 [/SUP], R Anju Rajan[SUP] 3 [/SUP], Blessy M Mani[SUP] 4 [/SUP], Muhasin Asaf[SUP] 5 [/SUP], Amit Kumar Pandey[SUP] 1 6 [/SUP]
Affiliations
- PMID: 34903944
- PMCID: PMC8654767
- DOI: 10.14202/vetworld.2021.2817-2826
Abstract
The recent coronavirus disease (COVID-19) outbreak is one of its kind in the history of public health that has created a major global threat. The causative agent, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a zoonotic source and hence, reverse zoonosis (disease transmission from humans to animals) increases the risk and rate of SARS-CoV-2 infection. Serological and molecular analyses and experimental infection studies have identified SARS-CoV-2 infection in several animal species in various countries. Different domestic and wild animals, including cats, dogs, tigers, lions, puma, snow leopard, minks, and pet ferrets, are infected naturally with SARS-CoV-2, mostly through suspected human to animal transmission. In addition, in vivo experimental inoculation studies have reported the susceptibility of cats, ferrets, hamsters, Egyptian fruit bats, and non-human primates to the virus. These experimentally infected species are found to be capable of virus transmission to co-housed animals of the same species. However, SARS-CoV-2 showed poor replication in livestock species such as pigs, chickens, and ducks with no detection of viral RNA after the animals were deliberately inoculated with the virus or exposed to the infected animals. As the pets/companion animals are more susceptible to COVID-19, the infection in animals needs an in-depth and careful study to avoid any future transmissions. The one health approach is the best inter-disciplinary method to understand the consequences of viral spread and prevention in novel host populations for the betterment of public health. Further in this review, we will explain in detail the different natural and experimentally induced cases of human to animal SARS-CoV-2 infection.
Keywords: mink; non-human primate; one health; reverse zoonosis; severe acute respiratory syndrome coronavirus 2.