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Viral and Bacterial Etiologies of Acute Respiratory Infections Among Children Under 5 Years in Senegal

tetano

Editor, Senior Moderator
Microbiol Insights. 2018 Feb 13;11:1178636118758651. doi: 10.1177/1178636118758651. eCollection 2018.
[h=1]Viral and Bacterial Etiologies of Acute Respiratory Infections Among Children Under 5 Years in Senegal.[/h] Assane D[SUP]1[/SUP], Makhtar C[SUP]1[/SUP], Abdoulaye D[SUP]1[/SUP], Amary F[SUP]2[/SUP], Djibril B[SUP]3[/SUP], Amadou D[SUP]1[/SUP], Niokhor DJB[SUP]4[/SUP], Amadou D[SUP]5[/SUP], Cheikh L[SUP]6[/SUP], Ndongo D[SUP]2[/SUP], Mbayame N[SUP]2[/SUP], Lamine F[SUP]7[/SUP], Bouh BCS[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Acute respiratory infections (ARIs) are the leading cause of infectious disease-related morbidity, hospitalization, and morbidity among children worldwide. This study aimed to assess the viral and bacterial causes of ARI morbidity and mortality in children under 5 years in Senegal. Nasopharyngeal samples were collected from children under 5 years who had ARI. Viruses and bacteria were identified using multiplex real-time reverse transcription-polymerase chain reaction and conventional biochemical techniques, respectively. Adenovirus was the most prevalent virus (50%; n = 81), followed by influenza virus (45.68%, n = 74), rhinovirus (40.12%; n = 65), enterovirus (25.31%; n = 41), and respiratory syncytial virus (16.05%; n = 26), whereas Streptococcus pneumoniae (17%; n = 29), Moraxella catarrhalis (15.43%; n = 25), and Haemophilus influenzae (8.02%; n = 13) were the most commonly isolated bacteria. Virus pathogens seem more likely to be more prevalent in our settings and were often associated with bacteria and S. pneumoniae (6%; 16) coinfection.


[h=4]KEYWORDS:[/h] Acute respiratory tract infections; bacteria; children <5 years; virus

PMID: 29467579 PMCID: PMC5815418 DOI: 10.1177/1178636118758651
 
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