tetano
Editor, Senior Moderator
Transbound Emerg Dis. 2018 Jul 17. doi: 10.1111/tbed.12959. [Epub ahead of print]
[h=1]Viral shedding of clade 2.3.4.4 H5 highly pathogenic avian influenza A viruses by American robins.[/h] Root JJ[SUP]1[/SUP], Bosco-Lauth AM[SUP]2[/SUP], Marlenee NL[SUP]2[/SUP], Bowen RA[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] American robins (Turdus migratorius) are commonly associated with farmsteads in the United States and have shown previous evidence of exposure to an H5 avian influenza A virus (IAV) near a poultry production facility affected by a highly pathogenic (HP) H5 virus in Iowa, USA during 2015. We experimentally infected American robins with three clade 2.3.4.4 HP H5 viruses (H5N2 and H5N8). A total of 22/24 American robins shed virus, and all three strains were represented. The highest virus titres shed were 10[SUP]4.3[/SUP] , 10[SUP]4.3[/SUP] and 10[SUP]4.8[/SUP] PFU/ml, associated respectively with viruses isolated from poultry, a captive gyrfalcon (Falco rusticolus), and a Northern pintail (Anas acuta). Of those birds that shed, viral shedding was initiated 1 or 2 days post-infection (DPI) and shedding ceased in all birds by 7 DPI. This study adds an additional synanthropic wildlife species to a growing list of animals that can successfully replicate and shed IAVs.
[h=4]KEYWORDS:[/h] Turdus migratorius ; American robin; Avian influenza A virus; Biosecurity; Clade 2.3.4.4; Experimental infection; H5N2; H5N8; Highly pathogenic; Outbreak; Passerine
PMID: 30014592 DOI: 10.1111/tbed.12959
[h=1]Viral shedding of clade 2.3.4.4 H5 highly pathogenic avian influenza A viruses by American robins.[/h] Root JJ[SUP]1[/SUP], Bosco-Lauth AM[SUP]2[/SUP], Marlenee NL[SUP]2[/SUP], Bowen RA[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] American robins (Turdus migratorius) are commonly associated with farmsteads in the United States and have shown previous evidence of exposure to an H5 avian influenza A virus (IAV) near a poultry production facility affected by a highly pathogenic (HP) H5 virus in Iowa, USA during 2015. We experimentally infected American robins with three clade 2.3.4.4 HP H5 viruses (H5N2 and H5N8). A total of 22/24 American robins shed virus, and all three strains were represented. The highest virus titres shed were 10[SUP]4.3[/SUP] , 10[SUP]4.3[/SUP] and 10[SUP]4.8[/SUP] PFU/ml, associated respectively with viruses isolated from poultry, a captive gyrfalcon (Falco rusticolus), and a Northern pintail (Anas acuta). Of those birds that shed, viral shedding was initiated 1 or 2 days post-infection (DPI) and shedding ceased in all birds by 7 DPI. This study adds an additional synanthropic wildlife species to a growing list of animals that can successfully replicate and shed IAVs.
[h=4]KEYWORDS:[/h] Turdus migratorius ; American robin; Avian influenza A virus; Biosecurity; Clade 2.3.4.4; Experimental infection; H5N2; H5N8; Highly pathogenic; Outbreak; Passerine
PMID: 30014592 DOI: 10.1111/tbed.12959