tetano
Editor, Senior Moderator
Virol J
. 2024 Dec 31;21(1):340.
doi: 10.1186/s12985-024-02594-6. Molecular epidemiological analysis of Influenza viruses in Influenza-like illness cases: a retrospective study in Chongqing Hi-Tech Zone, China (2021-2024)
Wei Cai[SUP] #[/SUP][SUP] 1 [/SUP], Yuhang Deng[SUP] 1 [/SUP], Pan Xu[SUP] 1 [/SUP], Jianjiang Xue[SUP] 2 [/SUP]
Affiliations
Objectives: To analyze the molecular epidemiological characteristics of influenza viruses in influenza-like cases in Chongqing Hi-Tech Zone, China, to provide data support and a scientific basis for optimizing influenza prevention and control strategies in the region.
Materials and methods: A retrospective analysis was conducted on the molecular epidemiological characteristics of influenza viruses in influenza-like cases at a hospital in Chongqing Hi-Tech Zone from 2021 to 2024. Colloidal gold detection of viral antibodies, fluorescent PCR detection of nucleic acids, and gene sequencing were used to identify the different subtypes.
Results: Among 39,986 ILI specimens tested using the immunocolloid gold method, 6,616 influenza viruses were detected, with a detection rate of 16.54%. Infections included 4,464 influenza A viruses (67.50%), 2,033 influenza B viruses (30.73%), and 119 co-infections of influenza A and B viruses (1.77%).In this region, H3N2 was the predominant subtype of influenza A, and Victoria was the main subtype of influenza B.
Conclusion: Influenza epidemics in the winter and spring seasons in Chongqing Hi-Tech Zone were predominantly caused by influenza A, with influenza B also circulating. Influenza A strains were mainly H3N2, while influenza B strains were primarily Victoria.
Keywords: Influenza viruses; Influenza-like illness cases; Molecular epidemiological analysis; Prevention and control.
. 2024 Dec 31;21(1):340.
doi: 10.1186/s12985-024-02594-6. Molecular epidemiological analysis of Influenza viruses in Influenza-like illness cases: a retrospective study in Chongqing Hi-Tech Zone, China (2021-2024)
Wei Cai[SUP] #[/SUP][SUP] 1 [/SUP], Yuhang Deng[SUP] 1 [/SUP], Pan Xu[SUP] 1 [/SUP], Jianjiang Xue[SUP] 2 [/SUP]
Affiliations
- PMID: 39741357
- PMCID: PMC11687026
- DOI: 10.1186/s12985-024-02594-6
Objectives: To analyze the molecular epidemiological characteristics of influenza viruses in influenza-like cases in Chongqing Hi-Tech Zone, China, to provide data support and a scientific basis for optimizing influenza prevention and control strategies in the region.
Materials and methods: A retrospective analysis was conducted on the molecular epidemiological characteristics of influenza viruses in influenza-like cases at a hospital in Chongqing Hi-Tech Zone from 2021 to 2024. Colloidal gold detection of viral antibodies, fluorescent PCR detection of nucleic acids, and gene sequencing were used to identify the different subtypes.
Results: Among 39,986 ILI specimens tested using the immunocolloid gold method, 6,616 influenza viruses were detected, with a detection rate of 16.54%. Infections included 4,464 influenza A viruses (67.50%), 2,033 influenza B viruses (30.73%), and 119 co-infections of influenza A and B viruses (1.77%).In this region, H3N2 was the predominant subtype of influenza A, and Victoria was the main subtype of influenza B.
Conclusion: Influenza epidemics in the winter and spring seasons in Chongqing Hi-Tech Zone were predominantly caused by influenza A, with influenza B also circulating. Influenza A strains were mainly H3N2, while influenza B strains were primarily Victoria.
Keywords: Influenza viruses; Influenza-like illness cases; Molecular epidemiological analysis; Prevention and control.