tetano
Editor, Senior Moderator
Clinical Infectious Diseases
Virus Detection and Duration of Illness Among Patients With 2009 Pandemic Influenza A (H1N1) Virus Infection in Texas
1. Anil Suryaprasad1,2,
2. Oliver W. Morgan1,3,
3. Patrick Peebles4,
4. Agnes Warner5,
5. Tara K. Kerin6,
6. Mathew D. Esona6,
7. Michael D. Bowen4,
8. Wendy Sessions4,
9. Xiyan Xu6,
10. Theresa Cromeans6,
11. Fatimah Dawood1,4,
12. Trudi Shim7,
13. Manoj Menon8,
14. Jennifer R. Verani5,
15. Dean Erdman6,
16. Stephen Lindstrom4,
17. Vincent P. Fonseca7,
18. Alicia M. Fry4, and
19. Sonja J. Olsen3
+ Author Affiliations
1.
1Epidemic Intelligence Service, Scientific Education and Professional Development Program Office (Proposed), Centers for Disease Control and Prevention, Atlanta, Georgia
2.
2Division of Epidemiology and Disease Prevention, Indian Health Service, Albuquerque, New Mexico
3.
3Division of Emerging Infections and Surveillance Services, National Center for Emerging and Zoonotic Infectious Diseases (Proposed), Centers for Disease Control and Prevention, Atlanta, Georgia
4.
4Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia
5.
5Division of Bacterial Disease, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia
6.
6Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia
7.
7Texas State Department of Health Services, Austin, Texas
8.
8Division of Parasitic Disease, National Center for Global Health (Proposed), Centers for Disease Control and Prevention, Atlanta, Georgia
1. Correspondence: Anil Suryaprasad, M.D., Epidemic Intelligence Service Officer, 1600 Clifton Road, MS G-37, Atlanta, GA 30333 (asuryaprasad@cdc.gov).
Abstract
Knowledge from early outbreaks is limited regarding the virus detection and illness duration of the 2009 pandemic influenza A (H1N1) infections. During the period from April to May 2009 in Texas, we collected serial nasopharyngeal (NP) and stool specimens from 35 participants, testing by real-time reverse transcriptase-polymerase chain reaction (rRT-PCR) and culture. The participants were aged 2 months to 71 years; 25 (71%) were under 18. The median duration of measured fever was 3.0 days and of virus detection in NP specimens was 4.2 days; however, few specimens were collected between days 5?9. The duration of virus detection (4.2 days) was similar to the duration of fever (3.5 days) (RR, 1.14; 95% CI, .66?1.95; P = .8), but was shorter than the duration of cough (11.0 days) (RR, .41; 95% CI, .24?.68; P < .001). We detected viral RNA in two participants? stools. All cultures were negative. This investigation suggests that the duration of virus detection was likely similar to the seasonal influenza virus.
http://cid.oxfordjournals.org/content/52/suppl_1/S109.full
Virus Detection and Duration of Illness Among Patients With 2009 Pandemic Influenza A (H1N1) Virus Infection in Texas
1. Anil Suryaprasad1,2,
2. Oliver W. Morgan1,3,
3. Patrick Peebles4,
4. Agnes Warner5,
5. Tara K. Kerin6,
6. Mathew D. Esona6,
7. Michael D. Bowen4,
8. Wendy Sessions4,
9. Xiyan Xu6,
10. Theresa Cromeans6,
11. Fatimah Dawood1,4,
12. Trudi Shim7,
13. Manoj Menon8,
14. Jennifer R. Verani5,
15. Dean Erdman6,
16. Stephen Lindstrom4,
17. Vincent P. Fonseca7,
18. Alicia M. Fry4, and
19. Sonja J. Olsen3
+ Author Affiliations
1.
1Epidemic Intelligence Service, Scientific Education and Professional Development Program Office (Proposed), Centers for Disease Control and Prevention, Atlanta, Georgia
2.
2Division of Epidemiology and Disease Prevention, Indian Health Service, Albuquerque, New Mexico
3.
3Division of Emerging Infections and Surveillance Services, National Center for Emerging and Zoonotic Infectious Diseases (Proposed), Centers for Disease Control and Prevention, Atlanta, Georgia
4.
4Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia
5.
5Division of Bacterial Disease, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia
6.
6Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia
7.
7Texas State Department of Health Services, Austin, Texas
8.
8Division of Parasitic Disease, National Center for Global Health (Proposed), Centers for Disease Control and Prevention, Atlanta, Georgia
1. Correspondence: Anil Suryaprasad, M.D., Epidemic Intelligence Service Officer, 1600 Clifton Road, MS G-37, Atlanta, GA 30333 (asuryaprasad@cdc.gov).
Abstract
Knowledge from early outbreaks is limited regarding the virus detection and illness duration of the 2009 pandemic influenza A (H1N1) infections. During the period from April to May 2009 in Texas, we collected serial nasopharyngeal (NP) and stool specimens from 35 participants, testing by real-time reverse transcriptase-polymerase chain reaction (rRT-PCR) and culture. The participants were aged 2 months to 71 years; 25 (71%) were under 18. The median duration of measured fever was 3.0 days and of virus detection in NP specimens was 4.2 days; however, few specimens were collected between days 5?9. The duration of virus detection (4.2 days) was similar to the duration of fever (3.5 days) (RR, 1.14; 95% CI, .66?1.95; P = .8), but was shorter than the duration of cough (11.0 days) (RR, .41; 95% CI, .24?.68; P < .001). We detected viral RNA in two participants? stools. All cultures were negative. This investigation suggests that the duration of virus detection was likely similar to the seasonal influenza virus.
http://cid.oxfordjournals.org/content/52/suppl_1/S109.full