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Editor, Senior Moderator
Vitamin D Supplementation Does Not Increase Immunogenicity of Seasonal Influenza Vaccine in HIV-Infected Adults
Journal HIV Clinical Trials
Publisher Thomas Land Publishers Inc.
ISSN 1528-4336 (Print)
Subject Life Science, Medicine, Immunology and Infectious Disease and Microbiology and Virology
Issue Volume 12, Number 5 / Sept-Oct 2011
Category Original Article
Pages 275-276
DOI 10.1310/hct1205-275
Online Date Thursday, December 15, 2011
Authors
Curtis Cooper1, Anona Thorne2, on behalf of the Canadian HIV Trials Network (CTN) Influenza Vaccine Research Group
1The Ottawa Hospital Division of Infectious Diseases, University of Ottawa, Ottawa, Canada
2 The Canadian HIV Trials Network, Vancouver, Canada
Abstract
The influence of vitamin D on influenza vaccine immunogenicity in HIV was assessed using data from a phase 3, randomized trial conducted during the 2008?2009 influ-enza season. Thirty-three percent of participants were on supplemental vitamin D at baseline. Neither seroconversion nor seroprotection were predicted by vitamin D use for any of the 3 vaccine strains. There is no evidence of improved influenza vaccine immunogenicity with vitamin D supplementation in this HIV-positive population.
http://thomasland.metapress.com/content/hj45501801252v6n/
Journal HIV Clinical Trials
Publisher Thomas Land Publishers Inc.
ISSN 1528-4336 (Print)
Subject Life Science, Medicine, Immunology and Infectious Disease and Microbiology and Virology
Issue Volume 12, Number 5 / Sept-Oct 2011
Category Original Article
Pages 275-276
DOI 10.1310/hct1205-275
Online Date Thursday, December 15, 2011
Authors
Curtis Cooper1, Anona Thorne2, on behalf of the Canadian HIV Trials Network (CTN) Influenza Vaccine Research Group
1The Ottawa Hospital Division of Infectious Diseases, University of Ottawa, Ottawa, Canada
2 The Canadian HIV Trials Network, Vancouver, Canada
Abstract
The influence of vitamin D on influenza vaccine immunogenicity in HIV was assessed using data from a phase 3, randomized trial conducted during the 2008?2009 influ-enza season. Thirty-three percent of participants were on supplemental vitamin D at baseline. Neither seroconversion nor seroprotection were predicted by vitamin D use for any of the 3 vaccine strains. There is no evidence of improved influenza vaccine immunogenicity with vitamin D supplementation in this HIV-positive population.
http://thomasland.metapress.com/content/hj45501801252v6n/