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Weaker wave of swine flu will bring new challenges in 2010

Shiloh

Editor, Senior Moderator
Source: http://ultimosegundo.ig.com.br/pers...ina+trara+novos+desafios+em+2010+9253214.html

Google translation:

Weaker wave of swine flu will bring new challenges in 2010

22/12 - 19:42 - Fernanda Aranda, iG Sao Paulo


The acronym H1N1 threat was repeated in all languages during 2009. The first pandemic of the century has reached 207 countries and infected 220 thousand people in the world, 13% Brazilian.

In June 2010, a second season of influenza A, known as swine flu, should burst in the country estimates, however, important differences sight: a wave will be weaker and much less intriguing than the first.

In view of the experts consulted by iG, there are three main factors that point to this reality. The first is that scientists have begun to unravel some features of the virus that terrified the planet killing children, youth and pregnant women. The second is the availability of the vaccine, a major barrier to contain the infestation of contagion. "Moreover, the majority of the population has had contact with H1N1 and therefore is naturally immune. This makes the second wave weaker, "points as the third reason pulmonologist Edward Genofre, director of the Brazilian Thoracic Society.

While projections that speak softer contagion, the experts point out the obstacles that can complicate the "transfer" of H1N1 by Country "Genetic mutations of the virus may threaten the ongoing production of the vaccine," said the president of Brazilian Society of Infectious Diseases, Juv?ncio Furtado. One of the mutations have even been identified in Norway, China, Finland, France, Italy, Brazil, Japan, Mexico, Ukraine and USA and is being monitored by the Global Influenza Surveillance. So far the variation of the virus was not as a new version of disseminated disease. Another problem is touted by doctors to rush the population by the vaccine, as with yellow fever at the beginning of the year. "For now, no country in the world has a range of doses that would like to have. Therefore, the vaccinated group will be limited,
"said Jose Guedes, director of the Butantan Institute, responsible for producing national levels.

* Read an exclusive interview with the director of the Instituto Butantan


More scientific knowledge

If you can point to some advantage in world crisis faced by health authorities in the virus H1N1 in 2009 it will certainly be science. The speed with which the virus spread and lethality in public until then considered out of danger, as the young, culminated in thousands of scientific publications on the subject. In practical terms, this is already serving as a basis for further understanding of new mechanisms to treat disease.

Until November 2009, were 30,055 cases in Brazil is that, since July, only the most serious manifestations of swine flu, with hospital, went to the records. People who had milder symptoms are out of the count and they are now at the heart of the studies. Doctors try to decipher how it was so lethal H1N1 in a portion (1,632 deaths in the country) and another caused mild symptoms similar to those of a cold. In this line of scientific tests, the Epidemiological Surveillance Center of S?o Paulo (CVE) expects to find the initial findings already next year, with comparative analysis of fatal victims of the disease and who were unaware of the infection.

Exaggerated response

In addition to research living with a group of 17 researchers from the University of S?o Paulo (USP), led by pathologist Thais Mauad, used knowledge provided by the dead - the autopsies of victims of the virus to move-in early responses on how the body reacts in the presence of H1N1. The analysis showed that the body's response is very aggressive: the same antibodies that attempt to eliminate the virus injure the lung. Furthermore, with the disease, the path of the bacteria to the lung function is facilitated. The first results of research are in the next edition of the "American Journal of Respiratory and Critical Care Medicine.

The conclusions of the work were made by autopsy of 21 people killed by swine influenza in the city of Sao Paulo. "The one exception, all had some other disease (or heart or lung) or were pregnant and obese," said study author. These findings, as Thais, can be used for laboratories have diretrizaes for clinical trials with new drugs. Furthermore, they serve to health authorities to define, more clearly, the symptoms that characterize the patient as a suspect and priority of care.
During 2009, this information appeared in scales. It took two months of the current epidemic for children, youth, pregnant, obese, and signs such as diarrhea and shortness of breath intense emerged as features of influenza A H1N1.

New program

In addition to a more defined protocol of treatment of cases, the experience of 2009 also defined changes in the national program to combat influenza A. In terms proprocionar, the states of Rio Grande do Sul, Sao Paulo and Goias were the most affected by the flu. According to the coordinator of the Epidemiological Surveillance Ministry of Health, Eduardo Hage, it was agreed that these places will redesign their strategies to combat the spread of the virus.
"From the two review meetings with all State Health Departments, held in early December, states are readjust their plans, including expansion of hospital units (taken as a reference for healthcare) and laboratories for examinations "he said.
 
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