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What is the added benefit of oropharyngeal swabs compared to nasal swabs alone for respiratory virus detection in hospitalized children aged <10 years

tetano

Editor, Senior Moderator
J Infect Dis. 2015 May 5. pii: jiv265. [Epub ahead of print]
[h=1]What is the added benefit of oropharyngeal swabs compared to nasal swabs alone for respiratory virus detection in hospitalized children aged <10 years?[/h] Dawood FS[SUP]1[/SUP], Jara J[SUP]2[/SUP], Estripeaut D[SUP]3[/SUP], Vergara O[SUP]3[/SUP], Luciani K[SUP]4[/SUP], Corro M[SUP]4[/SUP], de Le?n T[SUP]5[/SUP], Salda?a R[SUP]5[/SUP], Castillo Baires JM[SUP]6[/SUP], Rauda Flores R[SUP]6[/SUP], Cazares RA[SUP]7[/SUP], Brizuela de Fuentes YS[SUP]7[/SUP], Franco D[SUP]8[/SUP], Gaitan M[SUP]8[/SUP], Schneider E[SUP]9[/SUP], Berman L[SUP]1[/SUP], Azziz-Baumgartner E[SUP]1[/SUP], Widdowson MA[SUP]1[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] We evaluated the added value of collecting both nasal and oropharyngeal swabs compared to nasal swabs alone for detection of common respiratory viruses by reverse-transcription polymerase chain reaction in hospitalized children aged <10 years. Nasal swabs had equal or greater sensitivity than oropharyngeal swabs for detection of respiratory syncytial virus, adenovirus, human metapneumoviruses, rhinovirus, and influenza viruses, but not parainfluenza viruses. The addition of an oropharyngeal swab compared to nasal swab alone increased detection of each respiratory virus by <10% in children aged <10 years.
Published by Oxford University Press on behalf of the Infectious Diseases Society of America 2015. This work is written by (a) US Government employee(s) and is in the public domain in the US.


PMID: 25943205 [PubMed - as supplied by publisher]
 
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