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When people recover from Ebola they are still infectious?

Giddy Up

Member
Does the scientific evidence prove that when people recover from Ebola they are still infectious? If this is true, is this not a huge problem for releasing people back into the community?
 
Re: When people recover from Ebola they are still infectious?

There is very solid evidence that men who recover are contagious for quite a time -- several months -- in semen.

To my knowledge, it has not been found to be contagious in other bodily fluids for any noteworthy amount of time after recovery. So not in sweat, saliva, mucous, feces, vomit, etc -- on those fronts, it appears currently that it is not contagious after recovery.

Sexual transmission could be an issue after recovery, though. So far, we've had very few cases here, so it has been easy to track -- and the one man who has survived in the US was himself a medical professional, so it probably wasn't a huge issue to communicate to him that sexual activity was risky for longer. If we ever have larger numbers of cases, I suspect that it will become a larger issue.
 
Re: When people recover from Ebola they are still infectious?

Is this not a huge secondary problem for re infection? Are they giving out condoms to the surviving men that leave the Ebola clinics in Africa? I don't think that condoms are widely available in those areas or affordable. Once you have had ebola would you not clinically classed as infectious like you are with HIV?
 
Re: When people recover from Ebola they are still infectious?

Yeah, wow. How will this play out in the next few months? What about men who have recovered and moved to areas where they aren't known and stigmatized?
 
Re: When people recover from Ebola they are still infectious?

What about the lady is she still infectious? How can you contain something like this when you are releasing people back into the public that has survived? Are they tracking everyone that has survived and left the clinics? I really do not see how this is going to be contained at all!
 
Re: When people recover from Ebola they are still infectious?

That's all a big question mark in Africa, at the moment -- to be honest, it's spreading regardless in the three nations hit hardest. There have been awareness campaigns on it, but I don't think I've seen any info or data on how successful they are. Somebody else here might have a better idea, but I suspect that at this point, things are so bad there that it's not the top concern. The healthcare systems as a whole are reeling, people can't get treatment for just about anything right now, and there isn't enough space for all of the known ebola patients who need treatment/isolation.

Here, we have so far had so few cases that it isn't so much an issue -- we've had exactly three patients in the US, and two were working with the epidemic in Africa, so already knew a lot about it. It's unlikely to get to that level of bad here, but the more patients get the disease, the more this form of transmission is obviously a concern. If we have a small number of patients, we can better inform and track them, but it would have to get much worse here for it to be a particular worry.

The situation in Africa is pretty much simply out of control, there are not the number of human resources there to do that work.
 
Re: When people recover from Ebola they are still infectious?

Five, I guess, I forgot about the patient who was in Nebraska, and Dr. Sacra in MA. Sleepy.

Thus far, all of our patients here have been healthcare workers brought back from doing aid in West Africa, with the exception of Mr. Duncan, who sadly died.
 
Re: When people recover from Ebola they are still infectious?

So the people who are returned to countries and survive are still infectious via sexual contact. If they have sexual contact with someone after they have recovered their partner can become infected with Ebola and the partner can then become highly infectious (not just sexual contact). This really is alarming I think! Or am I wrong?
 
Re: When people recover from Ebola they are still infectious?

Person to person transmission is so out of control in Liberia and Sierra Leone, I don't think this is anywhere close to a predominant mode of transmission -- most from reports indicate most acquire infection caring for ill loved ones.

From the article:
"It's becoming a bigger issue as the number of survivors increases," said Sheldon Yett, UNICEF's country representative in Liberia.

Yett said he's heard of instances when the virus has been spread through unprotected sex. "Sexual transmission is a reality," he said.


http://www.usatoday.com/story/news/...a-virus-condoms-sexual-transmission/16960093/
 
Re: When people recover from Ebola they are still infectious?

So if in a "convalescent male, the virus can persist in semen for at least 70 days; one study suggests persistence for more than 90 days" why if they have any chance of stopping this would anyone be released until they show NO ABILITY to infect another person? I know the logistics of holding a person for months is unattainable in Africa...
 
Re: When people recover from Ebola they are still infectious?

Person to person transmission is so out of control in Liberia and Sierra Leone, I don't think this is anywhere close to a predominant mode of transmission -- most from reports indicate most acquire infection caring for ill loved ones.

True, but this aspect sure makes it tough to really ever get a handle on the outbreak there. Bad enough that the P2P transmission is out of control, but to think that survivors can restart transmission in the near future :(
 
Re: When people recover from Ebola they are still infectious?

Not only in Africa... Is everyone going to be Ebola positive? Negative? Just like HIV?
 
Re: When people recover from Ebola they are still infectious?

Thanks, AD, I hadn't noticed the full text button on that one. I hope the persistence stays as temporary as it is now, (bad as that already is.)
 
Re: When people recover from Ebola they are still infectious?

So if in a "convalescent male, the virus can persist in semen for at least 70 days; one study suggests persistence for more than 90 days" why if they have any chance of stopping this would anyone be released until they show NO ABILITY to infect another person?

My understanding of this is that although Ebola virus particles have been detected in semen for some time after the infection is cleared in the rest of the body, there has not yet been a documented case of transmission by sexual contact during convalescence.

Having said that, there have "only" been a few thousand cases, 70%+ of whom have died -- so the number of men who have recovered is relatively small. Whether sexual transmission will turn into a problem is still not known, unfortunately.
 
Re: When people recover from Ebola they are still infectious?

I've been reading some of the blogs on the MSF website by various people. One of the doctors wrote about an individual who did recover and was released. They provide them with an ample supply of condoms and explain that they are able to pass the virus for several months. I don't know if any other treatment facilities are doing this but MSF is.
 
Re: When people recover from Ebola they are still infectious?

Sorry about my ignorance but what is "the rule of six"?
The "rule of six" has to do with viral replication. Each molecule in the protein coating of the virus associates with six nucleotides within the genome, during the process of replication. That's a very simplified explanation, but if you want more details, I can expand on it.

Edited to add--it doesn't appear the the filviruses (Ebola and Marburg) adhere to the rule of six.
 
Re: When people recover from Ebola they are still infectious?

This study gives some data on infectivity after convalescence.
http://jid.oxfordjournals.org/content/196/Supplement_2/S142.full


The finding of EBOV in breast milk raises the possibility of direct mother-to-child transmission. In fact, breastfed children of both of the mothers whose milk was later tested in this study died of laboratory-confirmed EHF during early stages of the outbreak. The isolation of virus from breast milk in one case even after clearance from the blood suggests that transmission may occur even during convalescence. It is possible that the mammary gland, like the gonads [5] and chambers of the eye [13, 14], is an immunologically protected site in which clearance of virus is delayed
 
Re: When people recover from Ebola they are still infectious?

Is there some kind of overview/abstract showing actual transmission of EVD from the various bodily fluids the virus is detected in?
 
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