tetano
Editor, Senior Moderator
World J Gastroenterol
. 2021 Jul 14;27(26):4160-4171.
doi: 10.3748/wjg.v27.i26.4160.
Inflammatory effect on the gastrointestinal system associated with COVID-19
Paulina Delgado-Gonzalez[SUP] 1 [/SUP], Carlos A Gonzalez-Villarreal[SUP] 2 [/SUP], Jorge A Roacho-Perez[SUP] 1 [/SUP], Adriana G Quiroz-Reyes[SUP] 1 [/SUP], Jose Francisco Islas[SUP] 1 [/SUP], Juan Luis Delgado-Gallegos[SUP] 1 [/SUP], Daniel Arellanos-Soto[SUP] 1 [/SUP], Kame A Galan-Huerta[SUP] 1 [/SUP], Elsa N Garza-Treviño[SUP] 3 [/SUP]
Affiliations
Abstract
The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) that causes coronavirus disease-2019 (COVID-19) has provoked a global pandemic, mainly affecting the respiratory tract; however, a percentage of infected individuals can develop gastrointestinal (GI) symptoms. Some studies describe the development of GI symptoms and how they affect the progression of COVID-19. In this review, we summarize the main mechanisms associated with gut damage during infection by SARS-CoV-2 as well as other organs such as the liver and pancreas. Not only are host factors associated with severe COVID-19 but intestinal microbiota dysbiosis is also observed in patients with severe disease.
Keywords: COVID-19; Gastrointestinal symptoms; Gastrointestinal system; SARS-CoV-2.
. 2021 Jul 14;27(26):4160-4171.
doi: 10.3748/wjg.v27.i26.4160.
Inflammatory effect on the gastrointestinal system associated with COVID-19
Paulina Delgado-Gonzalez[SUP] 1 [/SUP], Carlos A Gonzalez-Villarreal[SUP] 2 [/SUP], Jorge A Roacho-Perez[SUP] 1 [/SUP], Adriana G Quiroz-Reyes[SUP] 1 [/SUP], Jose Francisco Islas[SUP] 1 [/SUP], Juan Luis Delgado-Gallegos[SUP] 1 [/SUP], Daniel Arellanos-Soto[SUP] 1 [/SUP], Kame A Galan-Huerta[SUP] 1 [/SUP], Elsa N Garza-Treviño[SUP] 3 [/SUP]
Affiliations
- PMID: 34326616
- PMCID: PMC8311540
- DOI: 10.3748/wjg.v27.i26.4160
Abstract
The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) that causes coronavirus disease-2019 (COVID-19) has provoked a global pandemic, mainly affecting the respiratory tract; however, a percentage of infected individuals can develop gastrointestinal (GI) symptoms. Some studies describe the development of GI symptoms and how they affect the progression of COVID-19. In this review, we summarize the main mechanisms associated with gut damage during infection by SARS-CoV-2 as well as other organs such as the liver and pancreas. Not only are host factors associated with severe COVID-19 but intestinal microbiota dysbiosis is also observed in patients with severe disease.
Keywords: COVID-19; Gastrointestinal symptoms; Gastrointestinal system; SARS-CoV-2.