tetano
Editor, Senior Moderator
World Neurosurg
. 2020 May 29;S1878-8750(20)31165-7.
doi: 10.1016/j.wneu.2020.05.194. Online ahead of print.
COVID-19-associated Encephalitis Mimicking Glial Tumor: A Case Report
Ibrahim Efecan Efe[SUP] 1 [/SUP], Orhun Utku Aydin[SUP] 1 [/SUP], Alper Alabulut[SUP] 2 [/SUP], Ozgur Celik[SUP] 2 [/SUP], Kerameddin Aydin[SUP] 3 [/SUP]
Affiliations
Abstract
Background: Reports on neurologic manifestations of coronavirus disease 2019 (COVID-19) have attracted broad attention. We present the unusual case of COVID-19-associated encephalitis mimicking a glial tumor.
Case description: A 35-year-old woman presented with headache and seizures. T2 fluid-attenuated inverse recovery imaging showed hyperintensities in the left temporal lobe. Magnetic resonance spectroscopy showed an elevated choline peak. Imaging findings were suggestive of high-grade glioma. Antiepileptic medication failed to achieve seizure control. Left anterior temporal lobectomy was performed. The patient had no post-operative deficits and her symptoms completely improved. Histological examination revealed encephalitis. Post-operatively, our patient was tested positive for COVID-19.
Conclusions: Our case raises awareness of neurologic manifestations of the disease and their potential to mimic glial tumors. For prompt diagnosis and prevention of transmission, clinicians should consider COVID-19 in patients with similar presentation.
Keywords: COVID-19; SARS-CoV-2; coronavirus; encephalitis; spectroscopy.
. 2020 May 29;S1878-8750(20)31165-7.
doi: 10.1016/j.wneu.2020.05.194. Online ahead of print.
COVID-19-associated Encephalitis Mimicking Glial Tumor: A Case Report
Ibrahim Efecan Efe[SUP] 1 [/SUP], Orhun Utku Aydin[SUP] 1 [/SUP], Alper Alabulut[SUP] 2 [/SUP], Ozgur Celik[SUP] 2 [/SUP], Kerameddin Aydin[SUP] 3 [/SUP]
Affiliations
- PMID: 32479911
- DOI: 10.1016/j.wneu.2020.05.194
Abstract
Background: Reports on neurologic manifestations of coronavirus disease 2019 (COVID-19) have attracted broad attention. We present the unusual case of COVID-19-associated encephalitis mimicking a glial tumor.
Case description: A 35-year-old woman presented with headache and seizures. T2 fluid-attenuated inverse recovery imaging showed hyperintensities in the left temporal lobe. Magnetic resonance spectroscopy showed an elevated choline peak. Imaging findings were suggestive of high-grade glioma. Antiepileptic medication failed to achieve seizure control. Left anterior temporal lobectomy was performed. The patient had no post-operative deficits and her symptoms completely improved. Histological examination revealed encephalitis. Post-operatively, our patient was tested positive for COVID-19.
Conclusions: Our case raises awareness of neurologic manifestations of the disease and their potential to mimic glial tumors. For prompt diagnosis and prevention of transmission, clinicians should consider COVID-19 in patients with similar presentation.
Keywords: COVID-19; SARS-CoV-2; coronavirus; encephalitis; spectroscopy.