tetano
Editor, Senior Moderator
Zhonghua Liu Xing Bing Xue Za Zhi. 2020 Apr 1;41(0):E033. doi: 10.3760/cma.j.cn112338-20200302-00236. [Epub ahead of print]
[Investigation of an epidemic cluster caused by COVID⁃19 cases in incubation period in Shanghai].
[Article in Chinese; Abstract available in Chinese from the publisher]
Xiao WJ[SUP]1[/SUP], Gao Q[SUP]2[/SUP], Jin K[SUP]3[/SUP], Gong XH[SUP]1[/SUP], Han RB[SUP]1[/SUP], Jiang CY[SUP]1[/SUP], Jiang XJ[SUP]1[/SUP], Jin BH[SUP]1[/SUP], Fang QW[SUP]1[/SUP], Pan H[SUP]1[/SUP], Wu HY[SUP]1[/SUP], Sun XD[SUP]4[/SUP].
Author information
Abstract
in English, Chinese
Objective: To analyze the epidemiological characteristics of a cluster of 5 confirmed COVID⁃19 cases related with the transmission in incubation period of initial case, and find out the infection source and transmission chain.. Methods: According to "The Prevention and Control Protocol for Coronavirus Disease 2019 (Third Edition)" issued by the National Health Commission, a field epidemiological survey was conducted for the 5 cases in January 2020. Nasopharyngeal swabs and sputum samples were collected from them for the detection of 2019-nCoV by real time RT-PCR. Multi prevention and control measures were taken, such as tracking and screening close contacts, medical isolation observation, investigating the epidemiological link, analyzing transmission chain. Results: Case 1, who had common environmental exposure with other COVID⁃19 cases, got sick on 20 January, 2020 and was confirmed on 1 February. Case 2 became symptomatic on 22 January and was confirmed on 27 January. Case 3 got sick on 25 January and was confirmed on 30 January. Case 4 had illness onset on 20 January and was confirmed on 1 February. Case 5 got sick on 23 January and was confirmed on 31 January. Among the 5 cases, case 2 died and the illness of other cases were effectively controlled. After exclusion of other common exposure factors, case 1 had a 6-hour meeting with case 2 and case 3 on 19 January. Case 2 and case 3 might be infected by case 1 during the incubation period. It is the key point for epidemiological investigation. Conclusion: The epidemiological investigation indicates that the transmission might occur in the incubation period of COVID-19 case, close attention should be paid to it in future COVID-19 prevention and control.
KEYWORDS:
COVID-19; Epidemic cluster; Incubation period; Transmission
PMID:32234128DOI:10.3760/cma.j.cn112338-20200302-00236
[Investigation of an epidemic cluster caused by COVID⁃19 cases in incubation period in Shanghai].
[Article in Chinese; Abstract available in Chinese from the publisher]
Xiao WJ[SUP]1[/SUP], Gao Q[SUP]2[/SUP], Jin K[SUP]3[/SUP], Gong XH[SUP]1[/SUP], Han RB[SUP]1[/SUP], Jiang CY[SUP]1[/SUP], Jiang XJ[SUP]1[/SUP], Jin BH[SUP]1[/SUP], Fang QW[SUP]1[/SUP], Pan H[SUP]1[/SUP], Wu HY[SUP]1[/SUP], Sun XD[SUP]4[/SUP].
Author information
Abstract
in English, Chinese
Objective: To analyze the epidemiological characteristics of a cluster of 5 confirmed COVID⁃19 cases related with the transmission in incubation period of initial case, and find out the infection source and transmission chain.. Methods: According to "The Prevention and Control Protocol for Coronavirus Disease 2019 (Third Edition)" issued by the National Health Commission, a field epidemiological survey was conducted for the 5 cases in January 2020. Nasopharyngeal swabs and sputum samples were collected from them for the detection of 2019-nCoV by real time RT-PCR. Multi prevention and control measures were taken, such as tracking and screening close contacts, medical isolation observation, investigating the epidemiological link, analyzing transmission chain. Results: Case 1, who had common environmental exposure with other COVID⁃19 cases, got sick on 20 January, 2020 and was confirmed on 1 February. Case 2 became symptomatic on 22 January and was confirmed on 27 January. Case 3 got sick on 25 January and was confirmed on 30 January. Case 4 had illness onset on 20 January and was confirmed on 1 February. Case 5 got sick on 23 January and was confirmed on 31 January. Among the 5 cases, case 2 died and the illness of other cases were effectively controlled. After exclusion of other common exposure factors, case 1 had a 6-hour meeting with case 2 and case 3 on 19 January. Case 2 and case 3 might be infected by case 1 during the incubation period. It is the key point for epidemiological investigation. Conclusion: The epidemiological investigation indicates that the transmission might occur in the incubation period of COVID-19 case, close attention should be paid to it in future COVID-19 prevention and control.
KEYWORDS:
COVID-19; Epidemic cluster; Incubation period; Transmission
PMID:32234128DOI:10.3760/cma.j.cn112338-20200302-00236