Re: India Dengue 2013
THIRUVANANTHAPURAM, May 25, 2013
More dengue cases on city outskirts (Thiruvananthapuram, Kerala)
SPECIAL CORRESPONDENT
24 confirmed cases reported in district on Friday
Fever cases have begun to swamp wards in most hospitals in the city, with a significant number of patients requiring prolonged treatment and rest.
Along with intermittent rain, dengue cases have been showing a steep increase in the district in the past few days. Twenty-four confirmed cases were reported on Friday. On Thursday, 23 cases of dengue were confirmed, while on the day before, the figure was 16. The actual number of cases could be much more as many patients are getting treated in the private sector hospitals, which may not figure on the official list.
Since January this year, the district has reported nearly 850 cases of dengue and there have been six suspected dengue deaths. If till last year, the city Corporation bore the brunt of the dengue caseload, this time many cases are being reported from the periphery. Of the 24 dengue cases reported on Friday, only six were from Corporation wards. On Thursday too, only four out of 23 cases in the district were from the Corporation wards
...
http://www.thehindu.com/news/cities...ue-cases-on-city-outskirts/article4749716.ece
Health squads to combat dengue fever in Kerala
OUR BUREAU
THIRUVANANTHAPURAM, OCT. 21:
The city corporation proposes to deploy 5,000 health squads from November 1, State formation day, to detect and eliminate mosquito breeding areas.
The squads will begin visits to households in all 100 wards, according to an official spokesman.
This comes in the backdrop of possible threat of an epidemic outbreak since garbage mounds under various stages of decay are now getting exposed to northeast monsoon rain.
...
http://www.thehindubusinessline.com...bat-dengue-fever-in-kerala/article4019373.ece
SEROPREVALENCE OF DENGUE IN TERTIARY CARE CENTRE AT LUCKNOW (Uttar Pradesh)
Date : 24-05-2013
Shipra Singhal1, Krati R. Varshney2, Vineeta Mittal3, Y. I. Singh4.
Correspondence
Dr. Y. I. Singh,
Email :
botombas@gmail.com
INTRODUCTION: Dengue virus infection has emerged as notable public health problem in recent decades especially in the tropical and subtropical countries because of high mortality and morbidity associated with it 1. Dengue with its two severe clinical manifestations dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) is endemic in India and epidemics are frequently reported from many parts of India and abroad. 2 It infects 50-100 million people worldwide a year resulting in 12,500 to 25,000 annual deaths.3In India a recent epidemic was noted in Delhi, Lucknow and many other places in Northern India in year 2010.4Hence early and rapid laboratory diagnosis which is usually done by serology is crucial for Dengue patients. The present study reports a Dengue haemorrhagic fever outbreak in a periurban slum area of Lucknow, Uttar Pradesh, India from February 2010 to January 2011.
MATERIALS AND METHODS: Patients suspected to be as dengue patients, were included irrespective of their age and sex. They had come to the Tertiary care hospital with complaint of fever, headache, malaise, myalgia and arthralgia, or who developed a maculopapular rash on the 3rd or 4th day of illness. Others with haemorrhagic manifestations such as epistaxis, bleeding gums and conjunctival haemorrhage were also included in the study. The cases of DF and DHF were diagnosed as per the criteria laid down by WHO5 .
Blood samples were collected from 668 clinically suspected DF or DHF cases attending Tertiary care hospital in Lucknow from February 2010 to January 2011, with prior consent of the patients. Sera were separated from 668 patients and tested for dengue- specific IgM and IgG antibodies by immunochromatographic strip6.
It was found that the maximum prevalence was seen in months of Sep, Oct and Nov 2010.Age group of 10-30 years was most affected as 151 cases (58.07%). Tests conducted revealed that most patients had hypoproteinemia, thrombocytopenia with platelet counts varying from 50,000 - 1,00,000/mm3 and elevated liver enzymes. Out of 668 sera of suspected patients 183 (27.4%) were IgM positive which indicated recent dengue infection. Out of this 19% were also positive for IgG indicating convalescent phase. Besides these, 33.46% were only IgG positive which showed past infection with dengue. Rest of the other patients showed clinical manifestations of dengue with even low platelet counts but the serology was negative probably due to early investigations for antibody detection.
DISCUSSION: Lucknow is situated in North India on the bank of Gomti River. Thus there are lots of marshy places which provide excellent mosquito breeding places. Further, this may be partially attributed to the rapid unplanned urbanization with unchecked construction activities and poor sanitation facilities contributing fertile breeding grounds for mosquitoes. It is also true that an increase in the alertness among medical fraternity and the availability of diagnostic tools have contributed to the increased detection of cases.
In our study maximum prevalence was seen in months of Sep, Oct and Nov 2010 in the age group of 10-30 years as 151 cases (58.07%).It is consistent with other Indian studies, as most of them have reported 15 to 45 years as the most affected age group as cited by studies done in Central India, Delhi , Karnataka and 1,7,8. However in several International studies, dengue has been reported as mainly a pediatric public health problem 9. The youngest positive case was 5 years and oldest case was 70 years old.
In the present study, out of 668 sera of suspected patients 183 (27.4%) were IgM positive which indicated recent dengue infection .It is consistent with study done by PM Ukey et al. in which 31.3% patients were serologically positive for dengue infection1.
Out of this 19% were also positive for IgG indicating convalescent phase. Besides these, 33.46% were only IgG positive which showed past infection with dengue.
Analysis of the data was done on monthly basis.
Male to Female positivity for IgM was 2.25:1 .Male preponderance and the age group of 15-30 years indicate more transmission of dengue infections at work sites. It is congruent with several other studies from Delhi and Karnataka7,8. But in few reports both the sexes were equally affected1.
In the present study maximum dengue cases occurred during the post monsoon season, i.e., from September to November 2010 only. It is similar to most of the previous outbreaks in India and may be because this time period is very favorable season for high breeding of the vector, i.e., Aedes aegypti . The correlation between occurrence of dengue and monsoon season is further supported by similar findings from Delhi, Chandigarh and Ludhiana 7,10,11. This seasonal outbreak of disease transmission is very important at local level for effective control measures.
Preventive measures against dengue infection should come into full swing during water stagnation periods after the initial bouts of rainfall and at the end of monsoon..Dengue IgM sensitivity among the suspected cases indicates active dengue virus activity and more studies need to be done to identify circulating serotypes of dengue virus to design preventive strategies.
REFERENCES:
1. Ukey PM, Bondade SA, Paunipagar PV, Powar RM, Akulwar SL. Study of Seroprevalence of Dengue Fever in Central India .Indian J Community Med -2010;35(4): 517?9.
2. Gunasekaran P, Kaveri K, Mohana S. Dengue disease status in Chennai (2006-2008): A retrospective analysis. Indian J Med Res -2011;133(3): 322-5.
3. Garg A, Garg J, Rao Y. K. Prevalence of dengue among clinically suspected febrile episodes at a teaching hospital in North India Journal of Infectious Diseases and Immunity- 2011;3(5):85-9.
4. Dengue in South East Asian Region. A report by World Health Organization [Internet].2010[cited 2010 Feb 25] Available from
www.who.com
5. Dengue haemorrhagic fever: diagnosis, treatment, prevention and control. 2nd edition. Geneva : World Health organization[Internet].2013[cited 2013 May 14] Available from
www.who.int/csr/resources/publications/dengue/012-23.pdf
6. Andrea J. Cuzzubbo, Timothy P. Endy, Ananda Nisalak, Siripen Kalayanarooj, David W. Vaughn, Steven A. Ogata, et al. Use of Recombinant Envelope Proteins for Serological Diagnosis of Dengue Virus Infection in an Immunochromatographic Assay. Clin Diagn Lab Immunol. -2001; 8(6): 1150?5.
7. Gupta E, Dar L, Narang P, Srivastava VK, Broor S. Serodiagnosis of dengue during an outbreak at a tertiary care hospital in Delhi. Indian J Med Res-2005; 121(1):36-8.
8. Kumar A, Rao R, Pandit V, Shetty S, Bamigatti C, Samaraging CM . Clinical manifestation and trend of dengue cases admitted in tertiary care hospital, Udupi District, Karnataka. Ind. Jr. Comm. Med; 35(3):386-91.
9. Shah GS, Islam S, Das BK. Clinical and laboratory profile of dengue infection in children. Kathmandu University Med. J. -2006; 4(1): 40-3.
10. Ratho RK, Mishra B, Kaur J, Kakkar N, Sharma K . An outbreak of dengue fever in Peri Urban slums of Chandigarh, India, with special reference to entomological and climatic factors. Indian J.Med. Sci.-2005; 59(12): 519-27.
11. Varghese SR, Lal Madan, Oberoi Aroma (2003).Recurrence of Dengue Epidemic in Ludhiana. Jkscience -2006; 8(2):95-6.
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